Cancer is a chronic non-communicable disease associated with a high mortality burden. The prevalence of cancer is increasing rapidly worldwide. However, this scenario will be worse in low and ...middle-income countries such as Chile, where 70% of cancer deaths occur. The aim of this review was to assess the epidemiological scenario of cancer and its projection for the Chilean population. In Chile, 53,365 new cases of cancer were diagnosed in 2018, led by prostate, colorectal, breast, stomach, lung and gallbladder cancer. From 1986 to 2016, cancer increased by 109%. When we reviewed mortality by sex, stomach and prostate cancer were responsible for more than 30% of cancer deaths among men. However, for women the first three places were occupied by breast, colorectal and lung cancer, as in the rest of the world. Considering that 40% of cancers are related to unhealthy lifestyles, working on the prevention of modifiable risk factors represents an opportunity for the creation of public health policies that allow changes at the environmental and individual level.
Interventions aiming to reduce obesity and sedentary behaviors in young adults could be a feasible and effective approach to prevent cardiovascular diseases.
To evaluate the effect of a ...lifestyle-based intervention on reducing cardiovascular risk factors in university students.
Sixty university students aged 21 ± 1 years (n = 44 females) took part on a 17 weeks lifestyle intervention consisting in education about healthy lifestyles and physical training, during a curricular course about health promotion and healthy lifestyles. At baseline and at the end of the intervention participants completed a lifestyles questionnaire and provided fasting blood samples to quantify glucose and lipids profile.
After the intervention significant reductions in the prevalence of hyperglycemia (-10.0%), high blood pressure (-16.7%) and physical inactivity (-26.7%) were observed. Moreover, a significant reduction in body weight, waist circumference, blood pressure, total cholesterol, triglycerides and an increase in HDL cholesterol were observed after intervention.
The implementation of an intervention to promote healthy lifestyles is an effective way of reducing cardiovascular risk factors in university students.
Background: There are limited data concerning the incidence density (ID) of ATTRwt, AL and AA amyloidosis in the Argentinean population. Our aim was to estimate the ID of ATTRwt, AL and AA ...amyloidosis at the Hospital Italiano Medical Care Program in Buenos Aires, Argentina.
Methods: Population was all members of a hospital-based health maintenance organization who were affiliated since January 2006 to December 2014. Each person was followed contributing time at risk since January 2006 or enrollment date to the final date. Incident cases of amyloidosis were captured from the institutional registry of amyloidosis. Incidence rate was calculated with 95% confidence intervals.
Results: During the nine-year study period, there were 15 patients with ATTRwt, 12 with AL and 2 with AA amyloidosis for 1 105 152 person-years of follow-up. The crude ID of ATTRwt amyloidosis was 13.5 (95%CI 8.1-22.4), that of AL amyloidosis 11 (95%CI: 6-19) and that of AA amyloidosis 1.8 (95%CI: 0.5-7.2) per 1 000 000 person-years. The highest ID was found in men (31.7 for ATTRwt, 15.9 for AL and 2.27 for AA amyloidosis per 1 000 000 person-years). The ID adjusted to the population of the city of Buenos Aires was 6.46 (95%CI: 3.17-9.74) for ATTRwt, 6.13 (95%CI: 2.57-9.7) for AL and 1.21 (95%CI: 0.56 to 2.99) for AA amyloidosis.
Conclusions: This is the first paper to report the incidence density of ATTRwt, AL and AA amyloidosis in Latin America. Our results are consistent with other studies from other regions. Although systemic amyloidosis is a rare disease, it is a major health problem because of its morbi-mortality.
•Historical data was used to determine the latitudinal distribution of zooplankton and the influence of the islands.•The archipelago influences the abundance favorably, but it does not affect the ...diversity.•Species with wide intervals of distribution are in the central area of the gulf and in the southern part of the domain.•At large scale, the distribution and abundance of zooplankton were consistent with the predictions of the Mid-Domain Effect•At smaller scales, the distribution and abundance of zooplankton are conditioned by the hydrodynamic characteristics of the gulf.
The upper Gulf of California is one of the most energetic regions owing to its tidal range and strong tidal currents, making the upper gulf and the archipelago zone highly turbulent regions; the abundance of zooplankton should be associated with mixing phenomena. We aimed to determine the latitudinal distribution of zooplanktonic organisms in this region and the influence of the islands on their distribution and abundance using historical data. Distribution of abundance followed the current patterns, the archipelago influences abundance favorably but does not affect diversity. Latitudinal zooplankton richness had a quasi-parabolic shape. A decrease in richness was observed at 27.5°N, in the archipelago region, with maximum richness at 26.5°N and 28.5°N. The distribution of latitudinal ranges is consistent with geometric constraints models; taxa with wide ranges are in the central area, while those with narrow ranges are near the boundaries and the Upper Gulf. Zooplankton responds in some way to the existence of the southern boundary as shown by the decrease of richness in this region. At the whole scale of the Gulf, the distribution of richness followed geometric constraints model, while at smaller scales, distribution and abundance are conditioned by the hydrodynamics of the Gulf. We compared zooplankton spatial distribution with Sea Level Anomaly, Sea Surface Temperature, and Chlorophyll-a concentrations from Copernicus to establish relationships between these factors. We performed Cluster and Redundancy Analysis to characterize similarities between stations in terms of biomass and taxon composition and to assess the importance of environmental variables on the distribution of zooplankton.
Background: Walking pace is a well-known indicator of physical capability, but it is also a strong predictor of type 2 diabetes (T2D). However, there is a lack of evidence on the association between ...walking pace and T2D, specifically, within developing countries such as Chile. Aim: To investigate the association between self-reported walking pace and T2D in the Chilean adult population. Methods: 5520 Chilean participants (aged 15 to 90 years, 52.1% women) from the Chilean National Health Survey 2016–2017 were included in this cross-sectional study. Both walking pace (slow, average, and brisk) and diabetes data were collected through self-reported methods. Fasting blood glucose (reported in mg/dl) and glycosylated haemoglobin A (HbA1c) scores were determined via blood exams. Results: In the unadjusted model, and compared to people who reported a slow walking pace, those with average and brisk walking pace had lower blood glucose levels (β = −7.74 mg/dL (95% CI: −11.08 to −4.40) and β = −11.05 mg/dL (95% CI: −14.36 to −7.75), respectively) and lower HbA1c (β = −0.34% (95% CI: −0.57 to −0.11) and β= −0.72% (95% CI: −0.94 to −0.49)), respectively. After adjusting for sociodemographic, Body Mass Index and lifestyle factors, the association between glycaemia and HbA1c remained only for brisk walkers. Both the average and brisk walker categories had lower odds of T2D (OR: 0.59 (95% CI: 0.41 to 0.84) and (OR 0.48 (95% CI: 0.30 to 0.79), respectively). Conclusion: Brisk walkers were associated with lower blood glucose and HbA1c levels. Moreover, average to brisk walking pace also showed a lower risk for T2D.
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