Realizing Refsdal's original idea from 1964, we present estimates of the Hubble constant that are complementary to, and potentially competitive with, those of other cosmological probes. We use the ...observed positions of 89 multiple images, with extensive spectroscopic information, from 28 background sources and the measured time delays between the images S1-S4 and SX of supernova "Refsdal" (z = 1.489), which were obtained thanks to Hubble Space Telescope deep imaging and Multi Unit Spectroscopic Explorer data. We extend the strong-lensing modeling of the Hubble Frontier Fields galaxy cluster MACS J1149.5+2223 (z = 0.542), published by Grillo et al. (2016), and explore different ΛCDM models. Taking advantage of the lensing information associated to the presence of very close pairs of multiple images at various redshifts, and to the extended surface brightness distribution of the SN Refsdal host, we can reconstruct the total mass-density profile of the cluster very precisely. The combined dependence of the multiple-image positions and time delays on the cosmological parameters allows us to infer the values of H0 and m with relative (1 ) statistical errors of, respectively, 6% (7%) and 31% (26%) in flat (general) cosmological models, assuming a conservative 3% uncertainty on the final time delay of image SX and, remarkably, no priors from other cosmological experiments. Our best estimate of H0, based on the model described in this work, will be presented when the final time-delay measurement becomes available. Our results show that it is possible to utilize time delays in lens galaxy clusters as an important alternative tool for measuring the expansion rate and the geometry of the universe.
ABSTRACT
We present a VLT/X-Shooter spectroscopy of the Lyman continuum (LyC) emitting galaxy Ion2 at z = 3.2121 and compare it to that of the recently discovered strongly lensed LyC emitter at ...z = 2.37, known as the Sunburst arc. Three main results emerge from the X-Shooter spectrum: (a) the Ly α has three distinct peaks with the central one at the systemic redshift, indicating a ionized tunnel through which both Ly α and LyC radiation escape; (b) the large O32 oxygen index (O iii λλ4959, 5007/O ii λλ3727, 3729) of $9.18_{-1.32}^{+1.82}$ is compatible to those measured in local (z ∼0.4) LyC leakers; (c) there are narrow nebular high-ionization metal lines with σv < 20 km s−1, which confirms the presence of young hot, massive stars. The He iiλ1640 appears broad, consistent with a young stellar component including Wolf–Rayet stars. Similarly, the Sunburst LyC emitter shows a triple-peaked Ly α profile and from VLT/MUSE spectroscopy the presence of spectral features arising from young hot and massive stars. The strong lensing magnification, (μ > 20), suggests that this exceptional object is a gravitationally bound star cluster observed at a cosmological distance, with a stellar mass M ≲ 107 M⊙ and an effective radius smaller than 20 pc. Intriguingly, sources like Sunburst but without lensing magnification might appear as Ion2-like galaxies, in which unresolved massive star clusters dominate the ultraviolet emission. This work supports the idea that dense young star clusters can contribute to the ionization of the IGM through holes created by stellar feedback.
We report the spectroscopic confirmation of 22 new multiply lensed sources behind the Hubble Frontier Field (HFF) galaxy cluster MACS J0416.1−2403 (MACS 0416), using archival data from the Multi Unit ...Spectroscopic Explorer (MUSE) on the VLT. Combining with previous spectroscopic measurements of 15 other multiply imaged sources, we have obtained a sample of 102 secure multiple images with measured redshifts, the largest to date in a single strong lensing system. The newly confirmed sources are largely low-luminosity Lyman-α emitters with redshift in the range 3.08−6.15 . With such a large number of secure constraints, and a significantly improved sample of galaxy members in the cluster core, we have improved our previous strong lensing model and obtained a robust determination of the projected total mass distribution of MACS 0416. We find evidence of three cored dark-matter halos, adding to the known complexity of this merging system. The total mass density profile, as well as the sub-halo population, are found to be in good agreement with previous works. We update and make public the redshift catalog of MACS 0416 from our previous spectroscopic campaign with the new MUSE redshifts. We also release lensing maps (convergence, shear, magnification) in the standard HFF format.
Eph receptors play important functions in developmental processes and diseases and among them EphA2 is well known for its controversial role in cancer. Drug discovery strategies are mainly centered ...on EphA2 extracellular ligand-binding domain however, the receptor also contains a largely unexplored cytosolic Sam (Sterile alpha motif) domain at the C-terminus. EphA2-Sam binds the Sam domain from the lipid phosphatase Ship2 and the first Sam domain of Odin. Sam-Sam interactions may be important to regulate ligand-induced receptor endocytosis and degradation i.e., processes that could be engaged against tumor malignancy.
We critically analyzed literature related to a) Eph receptors with particular emphasis on EphA2 and its role in cancer, b) Sam domains, c) heterotypic Sam-Sam interactions involving EphA2-Sam.
While literature data indicate that binding of EphA2-Sam to Ship2-Sam should largely generate pro-oncogenic effects in cancer cells, the correlation between EphA2- Sam/Odin-Sam1 complex and the disease is unclear. Recently a few linear peptides encompassing binding interfaces from either Ship2-Sam and Odin-Sam1 have been characterized but failed to efficiently block heterotypic Sam-Sam interactions involving EphA2-Sam due to the lack of a native like fold.
Molecule antagonists of heterotypic EphA2-Sam associations could work as potential anticancer agents or be implemented as tools to further clarify receptor functions and eventually validate its role as a novel target in the field of anti-cancer drug discovery. Due to the failure of linear peptides there is a crucial need for novel approaches, based on cyclic or helical molecules, to target Sam-Sam interfaces.
Abstract
We report on five compact, extremely young (<10 Myr) and blue (βUV < −2.5, Fλ = λβ) objects observed with VLT/Multi Unit Spectroscopic Explorer at redshifts 3.1169 and 3.235, in addition to ...three objects at z = 6.145. These sources are strongly magnified (3–40 times) by the Hubble Frontier Field galaxy clusters MACS J0416 and AS1063. Their delensed half-light radii (Re) are between 16 and 140 pc, the stellar masses are ≃1–20 × 106 M⊙, the magnitudes are mUV = 28.8–31.4 (−17 < MUV < −15) and specific star formation rates can be as large as ∼800 Gyr−1. Remarkably, the inferred physical properties of two objects are similar to those expected in some globular cluster formation scenarios, representing the best candidate proto-GCs discovered so far. Rest-frame optical high-dispersion spectroscopy of one of them at z = 3.1169 yields a velocity dispersion σv ≃ 20 km s−1, implying a dynamical mass dominated by the stellar mass. Another object at z = 6.145, with delensed MUV ≃ −15.3 (mUV ≃ 31.4), shows a stellar mass and a star formation rate surface density consistent with the values expected from popular GC formation scenarios. An additional star-forming region at z = 6.145, with delensed mUV ≃ 32, a stellar mass of 0.5 × 106 M⊙ and a star formation rate of 0.06 M⊙ yr−1 is also identified. These objects currently represent the faintest spectroscopically confirmed star-forming systems at z > 3, elusive even in the deepest blank fields. We discuss how proto-GCs might contribute to the ionization budget of the Universe and augment Lyα visibility during reionization. This work underlines the crucial role of JWST in characterizing the rest-frame optical and near-infrared properties of such low-luminosity high-z objects.
We study possible systematic effects on the values of the cosmological parameters measured through strong lensing analyses of the Hubble Frontier Field galaxy cluster MACS J1149.5+2223. We use the ...observed positions of a large set of spectroscopically selected multiple images, including those of supernova "Refsdal" with their published time delays. Starting from our reference model in a flat ΛCDM cosmology, published in Grillo et al. (2018), we confirm the relevance of the longest measurable time delay, between SX and S1, and an approximately linear relation between its value and that of H0. We perform true blind tests by considering a range of time delays around its original estimate of 345 10 days, as an accurate measurement of this time delay is still not known at the time of analysis and writing. We investigate separately the impact of a constant sheet of mass at the cluster redshift, of a power-law profile for the mass density of the cluster main halo and of some scatter in the cluster member scaling relations. Remarkably, we find that these systematic effects do not introduce a significant bias on the inferred values of H0 and m and that the statistical uncertainties dominate the total error budget: a 3% uncertainty on the time delay of image SX translates into approximately 6% and 40% (including both statistical and systematic 1 ) uncertainties for H0 and m, respectively. Furthermore, our model accurately reproduces the extended surface brightness distribution of the supernova host. We also present the interesting possibility of measuring the value of the equation-of-state parameter w of the dark energy density, currently with a 30% uncertainty.
We investigate the strongly lensed (
μ
≃ ×10 − 100) Lyman continuum (LyC) galaxy, dubbed Sunburst, at
z
= 2.37, taking advantage of a new accurate model of the lens. A characterization of the ...intrinsic (delensed) properties of the system yields a size of ≃3 sq. kpc, a luminosity of
M
UV
= −20.3, and a stellar mass of
M
≃ 10
9
M
⊙
; 16% of the ultraviolet light is located in a 3 Myr old gravitationally bound young massive star cluster (YMC), with an effective radius of ∼8 pc (corresponding to 1 milliarcsec without lensing) and a dynamical mass of ∼10
7
M
⊙
(similar to the stellar mass) – from which LyC radiation is detected (
λ
< 912 Å). The star formation rate and stellar mass surface densities for the YMC are Log
10
(Σ
SFR
M
⊙
yr
−1
kpc
−2
) ≃ 3.7 and Log
10
(Σ
M
M
⊙
pc
−2
) ≃ 4.1, with sSFR > 330 Gyr
−1
, consistent with the values observed in local young massive star clusters. The inferred outflowing gas velocity (> 300 km s
−1
) exceeds the escape velocity of the cluster. The resulting relative escape fraction of the ionizing radiation emerging from the entire galaxy is higher than 6−12%, whilst it is ≳46 − 93% if inferred from the YMC multiple line of sights. At least 12 additional unresolved star-forming knots with radii spanning the interval 3 − 20 pc (the majority of them likely gravitationally bound star clusters) are identified in the galaxy. A significant fraction (40−60%) of the ultraviolet light of the entire galaxy is located in such bound star clusters. In adopting a formation timescale of the star clusters of 20 Myr, a cluster formation efficiency Γ ≳ 30%. The star formation rate surface density of the Sunburst galaxy (Log
10
(Σ
SFR
) = 0.5
−0.2
+0.3
) is consistent with the high inferred Γ, as observed in local galaxies experiencing extreme gas physical conditions. Overall, the presence of a bursty event (i.e., the 3 Myr old YMC with large sSFR) significantly influences the morphology (nucleation), photometry (photometric jumps), and spectroscopic output (nebular emission) of the entire galaxy. Without lensing magnification, the YMC would be associated to an unresolved 0.5 kpc–size star-forming clump. The delensed LyC and UV magnitude
m
1600
(at 1600 Å) of the YMC are ≃30.6 and ≃26.9, whilst the entire galaxy has
m
1600
≃ 24.8. The Sunburst galaxy shows a relatively large rest-frame equivalent width of EW
rest
(H
β
+ O
III
λλ
4959, 5007) ≃ 450 Å, with the YMC contributing to ∼30% (having a local EW
rest
≃ 1100 Å) and ∼1% of the total stellar mass. If O-type (ionizing) stars are mainly forged in star clusters, then such engines were the key ionizing agents during reionization and the increasing occurrence of high equivalent width lines (H
β
+ O
III
) observed at
z
> 6.5 might be an indirect signature of a high frequency of forming massive star clusters (or high Γ) at reionization. Future facilities, which will perform at few tens milliarcsec resolution (e.g., VLT/MAVIS or ELT), will probe bound clusters on moderately magnified (
μ
< 5 − 10) galaxies across cosmic epochs up to reionization.
We carried out a detailed strong lensing analysis of a sub-sample of eight galaxy clusters of the Cluster Lensing And Supernova survey with Hubble (CLASH) in the redshift range of zcluster = 0.23 − ...0.59 using extensive spectroscopic information, primarily from the Multi Unit Spectroscopic Explorer (MUSE) archival data and complemented with CLASH-VLT redshift measurements. The observed positions of the multiple images of strongly lensed background sources were used to constrain parametric models describing the cluster total mass distributions. Different models were tested in each cluster depending on the complexity of its mass distribution and on the number of detected multiple images. Four clusters show more than five spectroscopically confirmed multiple image families. In this sample, we did not make use of families that are only photometrically identified in order to reduce model degeneracies between the values of the total mass of a cluster source redshifts, in addition to systematics due to the potential misidentifications of multiple images. For the remaining four clusters, we used additional families without any spectroscopic confirmation to increase the number of strong lensing constraints up to the number of free parameters in our parametric models. We present spectroscopic confirmation of 27 multiply lensed sources, with no previous spectroscopic measurements, spanning over the redshift range of zsrc = 0.7 − 6.1. Moreover, we confirm an average of 48 galaxy members in the core of each cluster thanks to the high efficiency and large field of view of MUSE. We used this information to derive precise strong lensing models, projected total mass distributions, and magnification maps. We show that, despite having different properties (i.e. number of mass components, total mass, redshift, etc.), the projected total mass and mass density profiles of all clusters have very similar shapes when rescaled by independent measurements of M200c and R200c. Specifically, we measured the mean value of the projected total mass of our cluster sample within 10 (20)% of R200c to be 0.13 (0.32) of M200c, with a remarkably small scatter of 5 (6)%. Furthermore, the large number of high-z sources and the precise magnification maps derived in this work for four clusters add up to the sample of high-quality gravitational telescopes to be used to study the faint and distant Universe.
We present Multi Unit Spectroscopic Explorer (MUSE) observations in the core of the Hubble Frontier Fields (HFF) galaxy cluster MACS J1149.5+2223, where the first magnified and spatially resolved ...multiple images of supernova (SN) "Refsdal" at redshift 1.489 were detected. Thanks to a Director's Discretionary Time program with the Very Large Telescope and the extraordinary efficiency of MUSE, we measure 117 secure redshifts with just 4.8 hr of total integration time on a single 1 arcmin super(2) target pointing. We spectroscopically confirm 68 galaxy cluster members, with redshift values ranging from 0.5272 to 0.5660, and 18 multiple images belonging to seven background, lensed sources distributed in redshifts between 1.240 and 3.703. Starting from the combination of our catalog with those obtained from extensive spectroscopic and photometric campaigns using the Hubble Space Telescope(HST), we select a sample of 300 (164 spectroscopic and 136 photometric) cluster members, within approximately 500 kpc from the brightest cluster galaxy, and a set of 88 reliable multiple images associated with 10 different background source galaxies and 18 distinct knots in the spiral galaxy hosting SN "Refsdal." We exploit this valuable information to build six detailed strong-lensing models, the best of which reproduces the observed positions of the multiple images with an rms offset of only 0".26. We use these models to quantify the statistical and systematic errors on the predicted values of magnification and time delay of the next emerging image of SN "Refsdal." We find that its peak luminosity should occur between 2016 March and June and should be approximately 20% fainter than the dimmest (S4) of the previously detected images but above the detection limit of the planned HST/WFC3 follow-up. We present our two-dimensional reconstruction of the cluster mass density distribution and of the SN "Refsdal" host galaxy surface brightness distribution. We outline the road map toward even better strong-lensing models with a synergetic MUSE and HST effort.
We present a detailed mass reconstruction and a novel study on the substructure properties in the core of the Cluster Lensing And Supernova survey with Hubble (CLASH) and Frontier Fields galaxy ...clusterMACS J0416.1-2403. We reproduce the measured positions of a set of 30 multiple images with a remarkable median offset of only 0.3 by means of a comprehensive strong lensing model comprised of two cluster dark-matter halos, represented by cored elliptical pseudo-isothermal mass distributions, and the cluster member components, parameterized with dual pseudo-isothermal total mass profiles. We investigate the galaxy contribution, both in terms of total and stellar mass, to the total mass budget of the cluster. Our findings of the location and shape of the cluster dark-matter halo density profiles and on the cluster substructures provide intriguing tests of the assumed collisionless, cold nature of dark matter and of the role played by baryons in the process of structure formation.
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