Superconductivity is among the most fascinating and well-studied quantum states of matter. Despite over 100 years of research, a detailed understanding of how features of the normal-state electronic ...structure determine superconducting properties has remained elusive. For instance, the ability to deterministically enhance the superconducting transition temperature by design, rather than by serendipity, has been a long sought-after goal in condensed matter physics and materials science, but achieving this objective may require new tools, techniques and approaches. Here, we report the transmutation of a normal metal into a superconductor through the application of epitaxial strain. We demonstrate that synthesizing RuO
thin films on (110)-oriented TiO
substrates enhances the density of states near the Fermi level, which stabilizes superconductivity under strain, and suggests that a promising strategy to create new transition-metal superconductors is to apply judiciously chosen anisotropic strains that redistribute carriers within the low-energy manifold of d orbitals.
Atomically thin ferromagnetic and conducting electron systems are highly desired for spintronics, because they can be controlled with both magnetic and electric fields. We ...present(SrRuO3)1−(SrTiO3)5superlattices and single-unit-cell-thickSrRuO3samples that are capped withSrTiO3. We achieve samples of exceptional quality. In these samples, the electron systems comprise only a singleRuO2plane. We observe conductivity down to 50 mK, a ferromagnetic state with a Curie temperature of 25 K, and signals of magnetism persisting up to approximately 100 K.
Taylor A, Wang D, Patel K, Whittall R, Wood G, Farrer M, Neely RDG, Fairgrieve S, Nair D, Barbir M, Jones JL, Egan S, Everdale R, Lolin Y, Hughes E, Cooper JA, Hadfield SG, Norbury G, Humphries SE. ...Mutation detection rate and spectrum in familial hypercholesterolaemia patients in the UK pilot cascade project.
Cascade testing using DNA‐mutation information is now recommended in the UK for patients with familial hypercholesterolaemia (FH). We compared the detection rate and mutation spectrum in FH patients with a clinical diagnosis of definite (DFH) and possible (PFH) FH. Six hundred and thirty‐five probands from six UK centres were tested for 18 low‐density lipoprotein receptor gene (LDLR) mutations, APOB p.Arg3527Gln and PCSK9 p.Asp374Tyr using a commercial amplification refractory mutation system (ARMS) kit. Samples with no mutation detected were screened in all exons by single strand conformation polymorphism analysis (SSCP)/denaturing high performance liquid chromatography electrophoresis (dHPLC)/direct‐sequencing, followed by multiplex ligation‐dependent probe amplification (MLPA) to detect deletions and duplications in LDLR.The detection rate was significantly higher in the 190 DFH patients compared to the 394 PFH patients (56.3% and 28.4%, p > 0.00001). Fifty‐one patients had inadequate information to determine PFH/DFH status, and in this group the detection rate was similar to the PFH group (25.5%, p = 0.63 vs PFH). Overall, 232 patients had detected mutations (107 different; 6.9% not previously reported). The ARMS kit detected 100 (44%) and the MLPA kit 11 (4.7%). Twenty‐eight (12%) of the patients had the APOB p.Arg3527Gln and four (1.7%) had the PCSK9 p.Asp374Tyr mutation. Of the 296 relatives tested from 100 families, a mutation was identified in 56.1%. In 31 patients of Indian/Asian origin 10 mutations (two previously unreported) were identified. The utility of the ARMS kit was confirmed, but sequencing is still required in a comprehensive diagnostic service for FH. Even in subjects with a low clinical suspicion of FH, and in those of Indian origin, mutation testing has an acceptable detection rate.
SrRuO3, a ferromagnet with an approximately 160 K Curie temperature, exhibits a T2-dependent dc resistivity below ≈ 30 K . Nevertheless, previous optical studies in the infrared and terahertz range ...show non-Drude dynamics at low temperatures, which seem to contradict Fermi-liquid predictions. In this work, we measure the low-frequency THz range response of thin films with residual resistivity ratios, ρ300K/ρ4K ≈ 74. At temperatures below 30 K, we find both a sharp zero frequency mode which has a width narrower than kBT/ℏ as well as a broader zero frequency Lorentzian that has at least an order of magnitude larger scattering. Both features have temperature dependences consistent with a Fermi liquid with the wider feature explicitly showing a T2 scaling. Above 30 K, there is a crossover to a regime described by a single Drude peak that we believe arises from strong interband electron-electron scattering. Such two channel Drude transport sheds light on reports of the violation of Matthiessen's rule and extreme sensitivity to disorder in metallic ruthenates.
Before Euro-American settlement, many Native American nations intercropped maize (
Zea mays
), beans (
Phaseolus vulgaris
), and squash (
Cucurbita pepo
) in what is colloquially called the “Three ...Sisters.” Here we review the historic importance and consequences of rejuvenation of Three Sisters intercropping (3SI), outline a framework to engage Native growers in community science with positive feedbacks to university research, and present preliminary findings from ethnography and a randomized, replicated 3SI experiment. We developed mutually beneficial collaborative research agendas with four Midwestern US Native American nations. Ethnographic data highlighted a culturally based respect for 3SI as living beings, the importance it holds for all cultural facets of these Native nations, and the critical impact the practice has on environmental sustainability. One concern expressed by Native growers during ethnographic research was improving soil health—part of the rationale for establishing the 3SI agronomic experiment. To address this, we collaboratively designed a 3SI experiment. After 1 year, 3SI increased short-term soil respiration by 24%, decreased salt-extractable nitrate by 54%, had no effect on soil microbial biomass (but increased its carbon-to-nitrogen ratio by 32%) compared to the average of monoculture crops. The overarching purpose of this collaborative project is to develop a deeper understanding of 3SI, its cultural importance to Native communities, and how reinvigorating the practice—and intercropping in general—can make agroecosystems more sustainable for people and the environment.
Zirconium oxide, or zirconia, when modified with anions such as sulfate ions forms a highly acidic or superacidic catalyst depending on the treatment conditions. This catalyst is found to be well ...suited for catalyzing reactions of industrial importance, e.g. hydrocarbon isomerization, methanol conversion to hydrocarbons, alkylation, acylation, esterification, etherification, condensation, nitration, cyclization, hydration–dehydration, carbonylation, oligomerization, Fischer–Tropsch reaction, cracking and hydrocracking reactions, methane oxidative coupling, thioacetalization, adamantylation, manufacture of hydrogen peroxide, etc. The surface properties of these catalysts can be further modified in conjunction with noble or transition metals as promoters as well as with carbon molecular sieves. This review highlights the chemistry and engineering aspects of sulfated zirconia catalyst and its modified forms.
Background The enteric nervous system (ENS) continues its structural and functional growth after birth, with formation of ganglia and the innervation of growing smooth muscle. However, little is ...known about factors in the postnatal intestine that influence these processes.
Methods We examined the presence and potential role of glial cell line‐derived nerve growth factor (GDNF) in the rat postnatal ENS using neonatal tissue, primary co‐cultures of the myenteric plexus, smooth muscle, and glial cells as well as cell lines of smooth muscle or glial cells.
Key Results Western blot analysis showed that GDNF and its co‐receptors rearranged during transfection (RET) and GDNF family receptor alpha‐1 were expressed in the muscle layer of the neonatal and adult rat intestine. Immunohistochemistry localized the receptors for GDNF to myenteric neurons, while GDNF was localized to smooth muscle cells. In a co‐culture model, GDNF but not nerve growth factor, brain derived neurotrophic factor or neurotrophin‐3 significantly increased neuronal survival and more than doubled the numbers of neurites in vitro. RT‐PCR, qPCR, Western blotting, ELISA, and immunocytochemistry as well as bioassays of neuronal survival and of RET phosphorylation all identified intestinal smooth muscle as the source of GDNF in vitro. GDNF also induced morphological changes in the structure and organization of neurons and axons, causing marked aggregation of neuronal cell bodies and collinear development of axons. As well, GDNF (50–150 ng mL−1) significantly increased 3H‐choline uptake and stimulated 3H‐acetylcholine release.
Conclusions & Inferences We conclude that GDNF derived from intestinal smooth muscle cells is a key factor influencing the structural and functional development of postnatal myenteric neurons.
The spatial scales of relativistic radio jets, probed by relativistic magneto-hydrodynamic (RMHD) jet launching simulations and by most very long baseline interferometry (VLBI) observations differ by ...an order of magnitude. Bridging the gap between these RMHD simulations and VLBI observations requires selecting nearby active galactic nuclei (AGN), the parsec-scale region of which can be resolved. The radio source 3C 84 is a nearby bright AGN fulfilling the necessary requirements: it is launching a powerful, relativistic jet powered by a central supermassive black hole, while also being very bright. Using 22 GHz globe-spanning VLBI measurements of 3C 84 we studied its sub-parsec region in both total intensity and linear polarisation to explore the properties of this jet, with a linear resolution of ∼0.1 parsec. We tested different simulation set-ups by altering the bulk Lorentz factor Γ of the jet, as well as the magnetic field configuration (toroidal, poloidal, helical). We confirm the persistence of a limb brightened structure, which reaches deep into the sub-parsec region. The corresponding electric vector position angles (EVPAs) follow the bulk jet flow inside but tend to be orthogonal to it near the edges. Our state-of-the-art RMHD simulations show that this geometry is consistent with a spine-sheath model, associated with a mildly relativistic flow and a toroidal magnetic field configuration.
The LOFAR Two-metre Sky Survey Shimwell, T. W.; Hardcastle, M. J.; Tasse, C. ...
Astronomy and astrophysics (Berlin),
03/2022, Volume:
659
Journal Article
Peer reviewed
Open access
In this data release from the ongoing LOw-Frequency ARray (LOFAR) Two-metre Sky Survey we present 120–168 MHz images covering 27% of the northern sky. Our coverage is split into two regions centred ...at approximately 12h45m +44°30′ and 1h00m +28°00′ and spanning 4178 and 1457 square degrees respectively. The images were derived from 3451 h (7.6 PB) of LOFAR High Band Antenna data which were corrected for the direction-independent instrumental properties as well as direction-dependent ionospheric distortions during extensive, but fully automated, data processing. A catalogue of 4 396 228 radio sources is derived from our total intensity (Stokes
I
) maps, where the majority of these have never been detected at radio wavelengths before. At 6″ resolution, our full bandwidth Stokes
I
continuum maps with a central frequency of 144 MHz have: a median rms sensitivity of 83 μJy beam
−1
; a flux density scale accuracy of approximately 10%; an astrometric accuracy of 0.2″; and we estimate the point-source completeness to be 90% at a peak brightness of 0.8 mJy beam
−1
. By creating three 16 MHz bandwidth images across the band we are able to measure the in-band spectral index of many sources, albeit with an error on the derived spectral index of > ± 0.2 which is a consequence of our flux-density scale accuracy and small fractional bandwidth. Our circular polarisation (Stokes
V
) 20″ resolution 120–168 MHz continuum images have a median rms sensitivity of 95 μJy beam
−1
, and we estimate a Stokes
I
to Stokes
V
leakage of 0.056%. Our linear polarisation (Stokes
Q
and Stokes
U
) image cubes consist of 480 × 97.6 kHz wide planes and have a median rms sensitivity per plane of 10.8 mJy beam
−1
at 4′ and 2.2 mJy beam
−1
at 20″; we estimate the Stokes
I
to Stokes
Q
/
U
leakage to be approximately 0.2%. Here we characterise and publicly release our Stokes
I
,
Q
,
U
and
V
images in addition to the calibrated
uv
-data to facilitate the thorough scientific exploitation of this unique dataset.
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