Bistratamide H was expeditiously synthesized using a new fluorous protecting group, 2‐(tris(perfluorodecyl)silyl)ethoxycarbonyl (FTeoc) via a preparation of thiazole amino acid by a modified ...Hantzsch's method. The intermediates of the synthesis were easily isolated by fluorous liquid–liquid extraction. The fluorous protecting group was removed from the precursor of bistratamide H with TBAF and the recovered fluorous fragment, tris(perfluorodecyl)silylfluoride, was reacted with vinyl magnesium chloride to give an intermediate in the synthesis of FTeoc reagent.
Adjustment disorders with obsessive compulsive state, withdrawal or depressed mood, accelarated by the social factors, have been increasing in number, among from younger population through mid-, or ...late adulthood. Behind them as described in this paper, unsolved conflicts between parents and children were found in great degree which led us to consider further upon the problems of the reconciliation between them. Many suggestive evidences were brought about to us from the related areas, i.e. linguistics, antholopology, psychopathology and others. Going back to our history, traditions, and early religions, we aimed to explore the archetype of the reconciliation and the meaning of the burden accompanying with it. The thema “reconciliation- sacrifice-revival” might be one of the archetypes we are interested in. Though various factors to be resolved as in our cases, reconciliation should have more basic role in our society. Reconciliation is not a passive ceremony to pass through, but it should be the active or positive field we have to face and get over for the succession of the law we have to carry on and develop.
High enantioselectivity (up to 94% ee) has been achieved in the protonation of samarium enolates which were generated by SmI
2-mediated reduction of 2-aryl-2-methoxycyclohexanones using a C
...2-symmetric chiral diol as a proton source.
Graphic
PDF
