Abstract
We report the first asteroseismic results obtained with the Hertzsprung Stellar Observations Network Group Telescope from an extensive high-precision radial-velocity observing campaign of ...the subgiant
μ
Herculis. The data set was collected during 215 nights in 2014 and 2015. We detected a total of 49 oscillation modes with
l
values from zero to three, including some
l
= 1 mixed modes. Based on the rotational splitting observed in
l
= 1 modes, we determine a rotational period of 52 days and a stellar inclination angle of 63°. The parameters obtained through modeling of the observed oscillation frequencies agree very well with independent observations and imply a stellar mass between 1.11 and 1.15
M
⊙
and an age of
Gyr. Furthermore, the high-quality data allowed us to determine the acoustic depths of the He
ii
ionization layer and the base of the convection zone.
We report the first asteroseismic results obtained with the Hertzsprung Stellar Observations Network Group Telescope from an extensive high-precision radial-velocity observing campaign of the ...subgiant Herculis. The data set was collected during 215 nights in 2014 and 2015. We detected a total of 49 oscillation modes with l values from zero to three, including some l = 1 mixed modes. Based on the rotational splitting observed in l = 1 modes, we determine a rotational period of 52 days and a stellar inclination angle of 63°. The parameters obtained through modeling of the observed oscillation frequencies agree very well with independent observations and imply a stellar mass between 1.11 and 1.15 M and an age of Gyr. Furthermore, the high-quality data allowed us to determine the acoustic depths of the He ii ionization layer and the base of the convection zone.
We report the first asteroseismic results obtained with the Hertzsprung SONG Telescope from an extensive high-precision radial-velocity observing campaign of the subgiant muHerculis. The data set was ...collected during 215 nights in 2014 and 2015. We detected a total of 49 oscillation modes with l values from 0 to 3, including some l = 1 mixed modes. Based on the rotational splitting observed in l = 1 modes, we determine a rotational period of 52 days and a stellar inclination angle of 63 degrees. The parameters obtained through modeling of the observed oscillation frequencies agree very well with independent observations and imply a stellar mass between 1.11 and 1.15M_sun and an age of 7.8+/-0.4 Gyr. Furthermore, the high-quality data allowed us to determine the acoustic depths of the He II ionization layer and the base of the convection zone.
To investigate (i) psychometric properties of the Danish version of the Caregiver Burden Scale, (ii) predictors of burden in caregivers of persons with stroke, spinal cord injury, or traumatic brain ...injury, and (iii) severity of caregiver burden, and compare level of severity of burden in caregivers of persons with stroke, spinal cord injury, or traumatic brain injury.
Cross-sectional study.
Pooled sample of 122 caregivers.
Psychometric properties including internal consistency, floor and ceiling effects, inter-item and item-total correlation were investigated using the Caregiver Burden Scale. Severity of burden was compared using Fisher's exact test and ANOVA, and predictors of burden were investigated using multiple linear regression models.
The total burden score exhibited good internal consistency (α = 0.93), with no floor or ceiling effects. Longer time as a caregiver was a significant predictor of higher total score. The majority (52.2%) reported a low level of caregiver burden (below cut-off of 2.00). Mean scores on the Caregiver Burden Scale were not significantly different among caregivers across diagnostic groups. Differences were found when comparing spinal cord injury caregivers with brain injury caregivers (traumatic brain injury and stroke, collectively), χ2(2) = 6.38, p = 0.04, as spinal cord injury caregivers were more likely to report low levels of burden.
Good psychometric properties were reported, and most caregivers reported a low level of burden, and longer time as a caregiver was associated with higher burden. Consequently, the Caregiver Burden Scale is a valid measure to use when measuring burden in caregivers of stroke, spinal cord injury, and traumatic brain injury patients.
•Commercial chicken breeds popular in organic production was compared.•Hellevad chickens showed higher body weight from weeks 5–17 of age.•Hellevad and Hisex chickens had 2-fold higher MBL serum ...concentration than Bovans.•The humoral response to IBDV and IBV vaccines varied largely between breeds.•The absolute numbers of circulating leukocytes varied largely between breeds.
Owing to the higher demands for avoiding medication and antibiotics, health status of the production animals plays an important role in the poultry industry, especially in organic poultry systems. Immunity plays a major role in keeping the host free from disease, and it is evident that the host’s genetic make-up influences immunity and disease resistance/susceptibility in chickens.
Previously, breeding strategies aimed at selection for resistance against specific diseases with the risk of creating less disease resistance against other pathogens. Changing breeding strategies towards selection of chickens with a more general and broad disease resistance or robustness may therefore improve the overall health status, animal welfare, and food security in the poultry production. The aim of this study was therefore to compare the immunocompetence of the presumed “robust” Hellevad chickens with two chicken lines widely used in organic production, Bovans Brown (Bovans) and Hisex White (Hisex). The chickens were subjected to a routine vaccination program comprising one parasite and four viral vaccines.
The current study indicates that considerable differences in immunocompetence may exist between commercial layer lines used in organic production. The Hellevad chickens were found to have higher body weight at the end of the experiment (17 weeks of age) than the other two lines. Furthermore, Hellevad and Hisex chickens were found to have higher levels of humoral innate immunity with regard to sample to positive ratio of natural antibodies in serum and concentration of mannose-binding lectin in serum as compared to Bovans. Moreover, indications of an inflammatory response were observed in the Bovans at week 5, corresponding to 1 week after vaccination with live infectious bursal disease virus. With regard to adaptive immune parameters such as IgY concentration in blood and infectious bursal disease virus (IBDV)-specific antibody titres, the Hellevad and Hisex chickens had lower levels than the Bovans. How the differences observed in growth and immune parameters in the three chicken lines influence the immune protection against infection needs to be studied further.
Highlights • A. galli infection influenced vaccine-induced immunity to Newcastle Disease (ND) in chickens. • Parasitized NDV vaccinated chickens showed lower titres of NDV specific IgG and lower ...frequencies NDV-specific T cells in peripheral blood than non-parasitized vaccinated controls. • Upon NDV challenge, viral genomes persisted in the oral cavity for a slightly longer period of time in A. galli -infected NDV vaccinees as compared to non-parasitized NDV vaccines indicating an impact of A-galli on vaccine-induced protective immunity.
PURPOSETo explore families' experiences of participating in a family intervention, targeting families living with the consequences of acquired brain injury (ABI) or spinal cord injury (SCI).MATERIALS ...AND METHODSIndividuals with ABI or SCI and their family members were recruited from a randomised controlled trial investigating the effectiveness of the manual-based family intervention, which consisted of eight weekly sessions. Semi-structured interviews were conducted with 16 families (n = 33). The data were analyzed through reflexive thematic analysis.RESULTSOne central theme was developed "A sense of belonging together again", describing the value of the reciprocal format of the family intervention, where individuals with ABI or SCI and their family members gained new insights into each other while building up their relationship. The central theme was supported by three additional themes: "Strengthened communication and emotional control", "Acknowledging the changed life situation" and "Being seen as a whole person".CONCLUSIONSThe family intervention supported the families to strengthen family cohesion and to be capable to manage the changed life situation. The findings emphasize the importance of a family-centered approach in neurorehabilitation, and how healthcare professionals play a significant role in facilitating families to achieve a balanced level of family cohesion.
Acquiring a traumatic injury constitutes a severe life change for the survivor, but also for the surrounding family. The paradigm of helping the family has primarily been on psychosocial ...interventions targeting caregivers. However, interventions including both survivor and caregivers should be an essential part of treatment, as the whole family's functional level and mental health can be affected. The current study protocol presents a manualized family intervention for families living with traumatic injury to the brain (TBI) or spinal cord (tSCI). The objectives are to investigate if the intervention improves quality of life (QoL) and decreases burden. It is hypothesized that the family intervention improves problem-solving strategies and family dynamics, which will reduce the burden. This may improve the caregivers' mental health, which will improve the support to the survivor and QoL.
The study is an interventional, two-arm, randomized controlled trial. During a 2-year period, a total of 132 families will be included. Participants will be recruited from East-Denmark. Inclusion criteria are (1) TBI or tSCI, (2) ≥ 18 years of age, (3) ≥ 6 months to ≤ 2 years since discharge from hospital, (4) ability to understand and read Danish, (5) cognitive abilities that enable participation, and (6) a minimum of one family member actively involved in the survivor's life. Exclusion criteria are (1) active substance abuse, (2) aphasia, (3) prior neurologic or psychiatric diagnose, and (4) history of violence. Within each disease group, families will be allocated randomly to participate in an intervention or a control group with a ratio 1:1. The intervention groups receive the family intervention consisting of eight sessions of 90 min duration. Families in the control groups receive 2 h of psychoeducation. All participants complete questionnaires on QoL, self-perceived burden, family dynamics, problem-solving strategies, mental health, and resilience at pre-intervention, post-intervention, and 6-month follow up.
If the intervention is found to have effect, the study will contribute with novel knowledge on the use of a manual-based intervention including the entire family. This would be of clinical interest and would help families living with the consequences of TBI or tSCI.
ClinicalTrials.gov, NCT03814876. Retrospectively registered on 24 January 2019.
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