A
bstract
In the recent paper
arXiv:1606.02921
, the two invariant actions for 6D
N
=
1
0
conformal supergravity were constructed in superspace, corresponding to the supersymmetrization of
C
3
and
C
...□
C
. In this paper, we provide the translation from superspace to the component formulation of superconformal tensor calculus, and we give the full component actions of these two invariants. As a second application, we build the component form for the supersymmetric
F
□
F
action coupled to conformal supergravity. Exploiting the fact that the
N
=
2
0
Weyl multiplet has a consistent truncation to
N
=
1
0
, we then verify that there is indeed only a single
N
=
2
0
conformal supergravity invariant and reconstruct most of its bosonic terms by uplifting a certain linear combination of
N
=
1
0
invariants.
The construction and reconstruction of meanings by learners requires that they actively seek to integrate new knowledge with knowledge already in their cognitive structure. Ausubel's assimilation ...theory of cognitive learning has been shown to be effective in guiding research and instructional design to facilitate meaningful learning (Ausubel, The psychology of meaningful verbal learning, New York: Grune and Stratton, 1963; Educational psychology: A cognitive view, New York: Holt, Rinehart and Winston, 1968; The acquisition and retention of knowledge, Dordrecht: Kluwer, 2000). Gowin's Vee heuristic has been employed effectively to aid teachers and students in understanding the constructed nature of knowledge (Gowin, Educating, Ithaca, NY: Cornell University Press, 1981). 'Situated learning' occurs when learning is by rote or at a lower level of meaningful learning. Concept mapping has been used effectively to aid meaningful learning with resulting modification of student's knowledge structures. When these knowledge structures are limited or faulty in some way, they may be referred to as Limited or Inappropriate Propositional Hierarchies (LIPH's). Conceptual change, or more accurately conceptual reconstrution, requires meaningful learning to modify LIPH's. Collaborative group learning facilitates meaningful learning and new knowledge construction. World-wide economic changes are forcing major changes in business and industry placing a premium on the power and value of knowledge and new knowledge production. These changes require changes in school and university education that centers on the nature and power of meaningful learning. New computer tools are available to facilitate teaching activities targeted at modifying LIPH's, and aiding meaningful learning in general.
Alkenones are biomarkers produced solely by algae in the order Isochrysidales that have been used to reconstruct sea surface temperature (SST) since the 1980s. However, alkenone-based SST ...reconstructions in the northern high latitude oceans show significant bias towards warmer temperatures in core-tops, diverge from other SST proxies in down core records, and are often accompanied by anomalously high relative abundance of the C
tetra-unsaturated methyl alkenone (%C
). Elevated %C
is widely interpreted as an indicator of low sea surface salinity from polar water masses, but its biological source has thus far remained elusive. Here we identify a lineage of Isochrysidales that is responsible for elevated C
methyl alkenone in the northern high latitude oceans through next-generation sequencing and lab-culture experiments. This Isochrysidales lineage co-occurs widely with sea ice in marine environments and is distinct from other known marine alkenone-producers, namely Emiliania huxleyi and Gephyrocapsa oceanica. More importantly, the %C
in seawater filtered particulate organic matter and surface sediments is significantly correlated with annual mean sea ice concentrations. In sediment cores from the Svalbard region, the %C
concentration aligns with the Greenland temperature record and other qualitative regional sea ice records spanning the past 14 kyrs, reflecting sea ice concentrations quantitatively. Our findings imply that %C
is a powerful proxy for reconstructing sea ice conditions in the high latitude oceans on thousand- and, potentially, on million-year timescales.
Within the framework of six-dimensional N=(1,0) conformal supergravity, we introduce new off-shell multiplets O⁎(n), where n=3,4,…, and use them to construct higher-rank extensions of the linear ...multiplet action. The O⁎(n) multiplets may be viewed as being dual to well-known superconformal O(n) multiplets. We provide prepotential formulations for the O(n) and O⁎(n) multiplets coupled to conformal supergravity. For every O⁎(n) multiplet, we construct a higher derivative invariant which is superconformal on arbitrary superconformally flat backgrounds. We also show how our results can be used to construct new higher derivative actions in supergravity.
IgM monoclonal gammopathy of undetermined significance (MGUS) and Waldenström macroglobulinemia (WM) represent a disease spectrum with highly varied therapeutic management, ranging from observation ...to chemoimmunotherapy. The current classification relies solely on clinical features and does not explain the heterogeneity that exists within each of these conditions. Further investigation is warranted to shed light on the biology that may account for the clinical differences.
We used bone marrow (BM) clonal CD19+ and/or CD138+ sorted cells, matched BM supernatant, and peripheral blood serum from 32 patients (7 MGUS, 25 WM) to perform the first multi-omics approach including whole-exome sequencing, RNA sequencing, proteomics, metabolomics, and mass cytometry.
We identified three clusters with distinct pathway activation, immune content, metabolomic, and clinical features. Cluster 1 included only patients with WM and was characterized by transcriptional silencing of genes involved in cell cycle and immune response, enrichment of mitochondrial metabolism, infiltration of senescent T effector memory cells, and aggressive clinical behavior. Genetic/structural alterations of TNFAIP3 were distinct events of this cluster. Cluster 2 comprised both MGUS and WM patients with upregulation of inflammatory response, senescence and glycolysis signatures, increased activated T follicular helper and T regulatory cells, and indolent clinical behavior. Cluster 3 also included both MGUS and WM patients and exhibited intermediate features, including proliferative and inflammatory signaling, as well as glycolysis and mitochondrial metabolism.
We have identified three distinct molecular clusters, suggesting a potential biologic classification that may have therapeutic implications.
Non-conformal supercurrents in six dimensions Kuzenko, Sergei M.; Novak, Joseph; Theisen, Stefan
The journal of high energy physics,
02/2018, Volume:
2018, Issue:
2
Journal Article
Peer reviewed
Open access
A
bstract
Non-conformal supercurrents in six dimensions are described, which contain the trace of the energy-momentum tensor and the gamma-trace of the supersymmetry current amongst their component ...fields. Within the superconformal approach to
N
=
1
,
0
supergravity, we present various distinct non-conformal supercurrents, one of which is associated with an
O
2
(or linear) multiplet compensator, while another with a tensor multiplet compensator. We also derive an infinite class of non-conformal supercurrents involving
O
n
multiplets with
n
> 2. As an illustrative example we construct the relaxed hypermultiplet in supergravity. Finally, we put forward a non-conformal supercurrent in the
N
=
2
0
supersymmetric case.
A
bstract
We develop a superfield approach to compute chiral anomalies in general
N
= (1,0) supersymmetric gauge theories in six dimensions. Within the harmonic-superspace formulation for these gauge ...theories, the anomalous contributions to the effective action only come from matter and ghost hypermultiplets. By studying the short-distance behaviour of the propagator for the hypermultiplet coupled to a background vector multiplet, we compute the covariant and consistent chiral anomalies. We also provide a superform formulation for the non-abelian anomalous current multiplet in general
N
= (1, 0) supersymmetric gauge theories.
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