Determination of prognostic factors influencing overall survival in high-grade brain Statistical analysis based on prognostic factors. The RSCRR from 2005-13 were treated 130 patients with brain ...tumors grade 3, the first phase of the combined treatment was surgery: total removal 28(21.5%) patients, subtotal 86(66.2%) patients, stereotacticbiopsy 16(12.3%). Women 68(52.3%), men 62(47.7%). Age patients from 40 to 60 years, 18 to 39 years (45.4%), 71-40years (54.6%). The average age 41.68 years, median 40.2. All patients were divided into classes RPA: I class 87(66.9%), class II 23(17.7%), class III 5(3.8%), class IV 15(11.5%). We used correlation analysis, estimates of cumulative survival by Kaplan-Meier and Coxregression analysis. The calculation of the immediate results of statistical analysis SPSS Reliable overall survival factors were age (r = 0,25; p <0,05) and the tumor size (r = 0,32; p 0,05). STB indicator of overall survival 60% of patients survived 5years, with the total removal of glioma100% over 5years (p = 0.004). low survival rates in patients >40years - less than 80% of the patients survived more than 5years, at a 40years was 9years, and <40years 13.6 years. 5year overall survival RPA I - 90%, RPA II III - 80%, VI - 18months. Overall survival of patients used radiotherapy with single dose 2-3 Gy (p = 0.975) Conducted data indicate the relevance to brain tumors grade 3 reliable overall survival factors, which include the age and size of the tumor. Important prognostic parameter for assessing survival is the amount of surgery performed, the basic principle is to remove as much tumor tissue as possible and maintaining healthy tissues.