Increased content of CD4
+
CD161
+
IL-17A
+
Th17 lymphocytes in the peripheral blood was found in patients with pulmonary tuberculosis irrespective of the clinical form (infiltrative, disseminated) ...and variant of the disease (drug-sensitive, drug-resistant). The elevated content of Th17 cells in pulmonary tuberculosis is associated with hypersecretion of Th17-associated cytokines IL-17A and IL-22
in vitro
that was most pronounced (in case of IL-17A) in patients with disseminated pulmonary tuberculosis.
The CERES/NA45 radial drift Time Projection Chamber Adamová, D.; Agakichiev, G.; Antończyk, D. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
08/2008, Volume:
593, Issue:
3
Journal Article
Peer reviewed
The design, calibration, and performance of the first radial drift Time Projection Chamber (TPC) are presented. The TPC was built and installed at the CERES/NA45 experiment at the CERN SPS in the ...late nineties, with the objective to improve the momentum resolution of the spectrometer. The upgraded experiment took data twice, in 1999 and in 2000. After a detailed study of residual distortions a spatial resolution of
340
μ
m
in the azimuthal and
640
μ
m
in the radial direction was achieved, corresponding to a momentum resolution of
Δ
p
/
p
=
(
1
%
·
p
/
GeV
)
2
+
(
2
%
)
2
.
Flow coefficients vn of the orders n = 1 – 6 are measured with the High-Acceptance Spectrometer (HADES) at GSI for protons, deuterons, and tritons as a function of centrality, transverse momentum, ...and rapidity in Au + Au collisions at √sNN = 2.4 GeV. Combining the information from the flow coefficients of all orders allows us to construct for the first time, at collision energies of a few GeV, a multidifferential picture of the angular emission pattern of these particles. It reflects the complicated interplay between the effect of the central fireball pressure on the emission of particles and their subsequent interaction with spectator matter. The high precision information on higher order flow coefficients is a major step forward in constraining the equation of state of dense baryonic matter.
The global polarization of Λ hyperons along the total orbital angular momentum of a relativistic heavy-ion collision is presented based on the high statistics data samples collected in Au+Au ...collisions at sNN=2.4 GeV and Ag+Ag at 2.55 GeV with the High-Acceptance Di-Electron Spectrometer (HADES) at GSI, Darmstadt. This is the first measurement below the strangeness production threshold in nucleon-nucleon collisions. Results are reported as a function of the collision centrality as well as a function of the hyperon's transverse momentum (pT) and rapidity (yCM) for the range of centrality 0–40%. We observe a strong centrality dependence of the polarization with an increasing signal towards peripheral collisions. For mid-central (20 – 40%) collisions the polarization magnitudes are 〈PΛ〉(%)=6.8±1.3(stat.)±2.1(syst.) for Au+Au and 〈PΛ〉(%)=6.2±0.4(stat.)±0.6(syst.) for Ag+Ag, which are the largest values observed so far. This observation thus provides a continuation of the increasing trend previously observed by STAR and contrasts expectations from recent theoretical calculations predicting a maximum in the region of collision energies about 3 GeV. The observed polarization is of a similar magnitude as predicted by 3D-fluid-dynamics and the UrQMD plus thermal vorticity model and significantly above results from the AMPT model.
We present a search for the e+e− decay of a hypothetical dark photon, also named U vector boson, in inclusive dielectron spectra measured by HADES in the p(3.5 GeV) + p, Nb reactions, as well as the ...Ar (1.756 GeV/u) + KCl reaction. An upper limit on the kinetic mixing parameter squared ϵ2 at 90% CL has been obtained for the mass range MU=0.02–0.55 GeV/c2 and is compared with the present world data set. For masses 0.03–0.1 GeV/c2, the limit has been lowered with respect to previous results, allowing now to exclude a large part of the parameter region favored by the muon g−2 anomaly. Furthermore, an improved upper limit on the branching ratio of 2.3×10−6 has been set on the helicity-suppressed direct decay of the eta meson, η→e+e−, at 90% CL.
.
The centrality determination for Au + Au collisions at 1.23
A
GeV, as measured with HADES at the GSI-SIS18, is described. In order to extract collision geometry related quantities, such as the ...average impact parameter or number of participating nucleons, a Glauber Monte Carlo approach is employed. For the application of this model to collisions at this relatively low centre-of-mass energy of
s
NN
=
2
.
42
GeV special investigations were performed. As a result a well defined procedure to determine centrality classes for ongoing analyses of heavy-ion data is established.
We present data on charged kaons (K±) and ϕ mesons in Au(1.23A GeV)+Au collisions. It is the first simultaneous measurement of K− and ϕ mesons in central heavy-ion collisions below a kinetic beam ...energy of 10A GeV. The ϕ/K− multiplicity ratio is found to be surprisingly high with a value of 0.52±0.16 and shows no dependence on the centrality of the collision. Consequently, the different slopes of the K+ and K− transverse-mass spectra can be explained solely by feed-down, which substantially softens the spectra of K− mesons. Hence, in contrast to the commonly adapted argumentation in literature, the different slopes do not necessarily imply diverging freeze-out temperatures of K+ and K− mesons caused by different couplings to baryons.
Employing the Bonn–Gatchina partial wave analysis framework (PWA), we have analyzed HADES data of the reaction p(3.5 GeV)+p→pK+Λ. This reaction might contain information about the kaonic cluster ...“ppK−” (with quantum numbers JP=0− and total isospin I=1/2) via its decay into pΛ. Due to interference effects in our coherent description of the data, a hypothetical K‾NN (or, specifically “ppK−”) cluster signal need not necessarily show up as a pronounced feature (e.g. a peak) in an invariant mass spectrum like pΛ. Our PWA analysis includes a variety of resonant and non-resonant intermediate states and delivers a good description of our data (various angular distributions and two-hadron invariant mass spectra) without a contribution of a K‾NN cluster. At a confidence level of CLs=95% such a cluster cannot contribute more than 2–12% to the total cross section with a pK+Λ final state, which translates into a production cross-section between 0.7 μb and 4.2 μb, respectively. The range of the upper limit depends on the assumed cluster mass, width and production process.
We present the first observation of K^{-} and ϕ absorption within nuclear matter by means of π^{-}-induced reactions on C and W targets at an incident beam momentum of 1.7 GeV/c studied with HADES ...at SIS18/GSI. The double ratio (K^{-}/K^{+})_{W}/(K^{-}/K^{+})_{C} is found to be 0.319±0.009(stat)_{-0.012}^{+0.014}(syst) indicating a larger absorption of K^{-} in heavier targets as compared to lighter ones. The measured ϕ/K^{-} ratios in π^{-}+C and π^{-}+W reactions within the HADES acceptance are found to be equal to 0.55±0.04(stat)_{-0.07}^{+0.06}(syst) and to 0.63±0.06(stat)_{-0.11}^{+0.11}(syst), respectively. The similar ratios measured in the two different reactions demonstrate for the first time experimentally that the dynamics of the ϕ meson in nuclear medium is strongly coupled to the K^{-} dynamics. The large difference in the ϕ production off C and W nuclei is discussed in terms of a strong ϕN in-medium coupling. These results are relevant for the description of heavy-ion collisions and the structure of neutron stars.
High-precision measurements of flow coefficients
v
n
(
n
=
1
-
4
) for protons, deuterons and tritons relative to the first-order spectator plane have been performed in Au+Au collisions at
s
NN
=
2.4
... GeV with the High-Acceptance Di-Electron Spectrometer (HADES) at the SIS18/GSI. Flow coefficients are studied as a function of transverse momentum
p
t
and rapidity
y
cm
over a large region of phase-space and for several classes of collision centrality. A clear mass hierarchy, as expected by relativistic hydrodynamics, is found for the slope of
v
1
,
d
v
1
/
d
y
′
|
y
′
=
0
where
y
′
is the scaled rapidity, and for
v
2
at mid-rapidity. Scaling with the number of nucleons is observed for the
p
t
dependence of
v
2
and
v
4
at mid-rapidity, which is indicative for nuclear coalescence as the main process responsible for light nuclei formation.
v
2
is found to scale with the initial eccentricity
⟨
ϵ
2
⟩
, while
v
4
scales with
⟨
ϵ
2
⟩
2
and
⟨
ϵ
4
⟩
. The multi-differential high-precision data on
v
1
,
v
2
,
v
3
, and
v
4
provides important constraints on the equation-of-state of compressed baryonic matter.
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