The proposed Long Baseline Neutrino Observatory (LBNO) initially consists of \(\sim 20\) kton liquid double phase TPC complemented by a magnetised iron calorimeter, to be installed at the Pyh\"asalmi ...mine, at a distance of 2300 km from CERN. The conventional neutrino beam is produced by 400 GeV protons accelerated at the SPS accelerator delivering 700 kW of power. The long baseline provides a unique opportunity to study neutrino flavour oscillations over their 1st and 2nd oscillation maxima exploring the \(L/E\) behaviour, and distinguishing effects arising from \(\delta_{CP}\) and matter. In this paper we show how this comprehensive physics case can be further enhanced and complemented if a neutrino beam produced at the Protvino IHEP accelerator complex, at a distance of 1160 km, and with modest power of 450 kW is aimed towards the same far detectors. We show that the coupling of two independent sub-MW conventional neutrino and antineutrino beams at different baselines from CERN and Protvino will allow to measure CP violation in the leptonic sector at a confidence level of at least \(3\sigma\) for 50\% of the true values of \(\delta_{CP}\) with a 20 kton detector. With a far detector of 70 kton, the combination allows a \(3\sigma\) sensitivity for 75\% of the true values of \(\delta_{CP}\) after 10 years of running. Running two independent neutrino beams, each at a power below 1 MW, is more within today's state of the art than the long-term operation of a new single high-energy multi-MW facility, which has several technical challenges and will likely require a learning curve.
One of the main goals of the Long Baseline Neutrino Observatory (LBNO) is to study the \(L/E\) behaviour (spectral information) of the electron neutrino and antineutrino appearance probabilities, in ...order to determine the unknown CP-violation phase \(\delta_{CP}\) and discover CP-violation in the leptonic sector. The result is based on the measurement of the appearance probabilities in a broad range of energies, covering t he 1st and 2nd oscillation maxima, at a very long baseline of 2300 km. The sensitivity of the experiment can be maximised by optimising the energy spectra of the neutrino and anti-neutrino fluxes. Such an optimisation requires exploring an extended range of parameters describing in details the geometries and properties of the primary protons, hadron target and focusing elements in the neutrino beam line. In this paper we present a numerical solution that leads to an optimised energy spectra and study its impact on the sensitivity of LBNO to discover leptonic CP violation. In the optimised flux both 1st and 2nd oscillation maxima play an important role in the CP sensitivity. The studies also show that this configuration is less sensitive to systematic errors (e.g. on the total event rates) than an experiment which mainly relies on the neutrino-antineutrino asymmetry at the 1st maximum to determine the existence of CP-violation.
In Ophthalmological Clinic of the District Bucharest Hospital, the authors studied 59 patients with herpetic keratitis, and keratouveitis treated with Zovirax (acyclovir). They try to prove with ...clinical arguments the efficacity of this treatment in different forms of herpetic keratitis. The authors consider the acyclovir like the election therapy of ocular herpes, because it determines the increase of ocular vision in almost cases with short average hospitalization.
