The paper claiming that HCQ lead to serious cardiovascular side effects caused ripple effects throughout the scientific community,1 and prompted the World Health Organization (WHO) to temporarily ...halt recruitment of the international Solidarity trial, evaluating the role of HCQ in COVID-19. 8 Most guidelines on retractions are given by the committee of publication ethics (COPE), which state that “editors should consider retracting a publication if they have clear evidence that the findings are unreliable, either as a result of major error (e.g., miscalculation or experimental error), or as a result of fabrication (e.g., of data) or falsification (e.g., image manipulation), it constitutes plagiarism, the findings have previously been published elsewhere without proper attribution to previous sources or disclosure to the editor, permission to republish, or justification (i.e., cases of redundant publication), it contains material or data without authorization for use, copyright has been infringed or there is some other serious legal issue (e.g., libel, privacy), it reports unethical research, it has been published solely based on a compromised or manipulated peer review process, the author(s) failed to disclose a major competing interest (a.k.a. conflict of interest) that, in the view of the editor, would have unduly affected interpretations of the work or recommendations by editors and peer reviewers. ...the past month has possibly witnessed the biggest attempted heist in the history of scientific publications, akin to the Cambridge Analytica fiasco during the American presidential elections in 2016.
By far the most common etiology that comes to mind when we imagine the pediatric retina is retinopathy of prematurity (ROP) which has been dealt with in great detail in this issue, including its ...epidemiology, pathogenesis, risk factors, imaging, screening, treatment, and outcomes by some of the masters in this field. The third epidemic of ROP is upon us, with increasing incidence being reported form the developing world, and has been attributed to the development of high-class neonatal intensive care units (NICUs) with resultant heightened survival of very premature infants. To overcome these obstacles, innovative screening models have been built using tele-ophthalmology, such that ophthalmic technicians are trained to use retinal imaging devices and transmit images to a nodal center where an ophthalmologist can interpret images and advise the next course of action in real time.
...repeated injections of anti-VEGF agents have raised concerns of increase in size of geographic atrophy in eyes with neovascular AMD. ...the available RPE65 gene therapy for Leber's congenital ...amaurosis has opened many exciting new possibilities for management of retinal dystrophies and restored faith in the approach we are taking toward managing these diseases. ...we are in an exciting era where rapid change is the only constant, especially when it comes to the field of vitreoretinal diseases.
After such exhaustive planning in designing these charts, it is hardly surprising that authors found that visual acuity measured using these seven new charts was very close to vision measured using ...the Early Treatment Diabetic Retinopathy Study English chart. ...in another paper in the current issue, Srinivasan et al. present a new near vision chart to measure the rate of reading in Kannada. ...India epitomizes unity in diversity, and it is high time that we gave greater importance to our regional languages for vision testing. 1.
Purpose: The aim of this study was to report results of macular hole closure, visual benefit and longitudinal changes in foveal architecture over 1 year following macular hole surgery with retinal ...massage. Methods: Records of patients with full thickness macular hole (FTMH) with minimum basal diameter of 550 μ who underwent vitrectomy, internal limiting membrane (ILM) peeling and retinal massage were drawn up. Retinal massage was performed after dye assisted ILM peeling, using a 27G flute needle with a long and soft silicone tip under air in a centripetal direction around the FTMH. At the end, 10% C3F8 gas was used as tamponade. The foveal contour at 1 year follow up was recorded based on its cross sectional appearance on OCT and was classified into U, V and irregular types of closure as previously described. Results: Forty-one eyes of 41 patients with a mean age of 70.4 ± 6.9 years were included. The mean preoperative vision was 0.99 ± 0.07 logMAR and mean maximum basal diameter of the FTMH was 835 ± 208 μ. Macular hole closure was seen in all patients at 1-month follow up. The BCVA improved to 0.5 ± 0.1 log MAR at 6 months (P < 0.001) and then stabilized. The U shaped closure was the commonest pattern (n = 22, 54%), followed by V-shaped closure (n = 16, 39%) while irregular closure was seen in 3 eyes (7%). Conclusion: Retinal massage after ILM peeling is a very simple, and as yet under-utilized manoeuvre that may improve hole closure rates and lead to potentially greater improvement in vision compared to existing techniques for large holes.
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