Effectiveness of the use of Ampullaria glauca snails caviar for correction of radiation-induced disturbances after external disposable γ-irradiation of rats in dose of 2.0 Gy was investigated. Under ...these experimental conditions membrane stabilizing and adaptogenic properties of snails caviar have been established. Also, in rats that were irradiated at 2.0 Gy and consumed caviar of snails, normalization of the functional state of thyroid, pancreas and adrenal glands were revealed. Application of Ampullaria glauca snail caviar leads to modification of radiation damage and can be used to correct radiogenic disturbances in organism that is irradiated in small doses.
Rationale Epicoccum tends to be found in grassland and agricultural areas and is a cause of exacerbation of allergic diseases in the summer-autumn period.
Base‐promoted cyclization of N‐Boc‐ω‐(4‐(chloromethyl)oxazol‐5‐yl)alkylamines led to the corresponding “dimerization” products containing fused 10‐, 12‐, and 14‐membered rings. Experimental data ...showed that the formation of these ring systems is favored over the corresponding 5‐/6‐/7‐membered ones, which was partially confirmed by DFT calculations; this effect was especially significant in the case of the 5‐/10‐membered pair.
Base‐promoted cyclization of N‐Boc‐ω‐(4‐(chloromethyl)oxazol‐5‐yl)alkylamines results in preferable formation of fused 10‐, 12‐, and 14‐membered rings over the corresponding 5‐, 6‐, and 7‐membered ones.
Multiple band patterns of DNA repeats in the 20-500-nucleotide range can be detected by digesting genomic DNA with short-cutting restriction endonucleases, followed by end labeling of the restriction ...fragments and fractionation in nondenaturing polyacrylamide gels. We call such band patterns obtained from genomic DNA "taxonprints" (Fedorov et al. 1992). Here we show that taxonprints for the taxonomic groups studied (mammals, reptiles, fish, insects-altogether more than 50 species) have the following properties: (1) All individuals from the same species have identical taxonprints. (2) Taxonprint bands can be subdivided into those specific for a single species and those specific for groups of closely related species, genera, and even families. (3) Each restriction endonuclease produces unique band patterns; thus, five to ten restriction enzymes (about 100 bands) may be sufficient for a statistical treatment of phylogenetic relationships based on polymorphisms of restriction endinuclease sites. We demonstrate that taxonprint analysis allows one to distinguish closely related species and to establish the degree of similarity among species and among genera. These characteristics make taxonprint analysis a valuable tool for taxonomic and phylogenetic studies.
Sedentary lifestyle, being a behavioral risk factor for chronic non-communicable diseases, is relevant for preventive medicine. A key role in the correction of behavioral risk factors for chronic ...non-communicable diseases is occupied by general medical practice, where the patient is continuously observed for many years. Increased physical activity reduces the risk of atherosclerosis, diseases of the musculoskeletal system, malignant tumors, has a positive effect on the psychological state of patients and reduces the overall morbidity and mortality. Increasing the reserves of the cardiorespiratory system of the body, physical activity improves the quality of life of patients and reduces the cost of medical care.
To effectively combat sedentary lifestyle, it is necessary to adequately motivate patients that can be achieved through routine counseling to enhance physical activity. The method of such consultation should take into account limited time of outpatient admission and all personal characteristics of patients (starting level of physical activity, health group and risk of disease).
The article presents a summary of modern scientific views in the field of increasing physical activity of patients, discusses current issues of counseling. The groups of patients with or without chronic diseases and the high risk of cardiovascular complications were discussed. The variant of rational outpatient counseling with the help of the algorithm of organization of physical activity mode, providing stratification of patients, planning, optimization and control of personal motor activity was presented. The proposed method of optimization of counseling successfully solves the problems of motivation, increase of physical activity and individual approach in outpatient practice.
Aim - to study the prevalence of syndromes of anxiety and depression in correlation with major risk factors (RF) of chronic noninfectious diseases among patients of the Samara region considering ...themselves healthy. Materials and methods. A comparative population-based cross-sectional study was based on a representative selection of patients (95 people) from the Samara region (rural and urban population) at the age of 19-68 years. Results. The study revealed a significant increase in the rates of fatigue, anxiety and depression in outpatients. The syndrome of anxiety of subclinical level was detected in 35.7% of patients, clinical level - in 23.2% of patients; the syndrome of subclinical depression was revealed in 21.0% of patients, and 4.2% had the clinical level. We discovered the correlation between the syndromes of anxiety and depression and the major RF of chronic noninfectious diseases and patient’s satisfaction with quality of medical care in the clinic. High levels of anxiety were more frequent in men, at older age, and were associated with physical inactivity. Severe depression more often occurred at older age and in the presence of hypercholesterolemia. The income level of the patient correlated with the level of stress exposure, physical activity and satisfaction with the work of the policlinics. We did not reveal the relationship between the syndromes of anxiety and/or depression and the level of income, degree of hypertension, social activity, smoking, alcohol consumption, and body mass index. Conclusion. The results indicate that the presence of the syndromes of anxiety and depression increases the risk of occurrence of other independent risk factors of chronic noninfectious diseases. The identified trends can serve as the basis for targeted screening programs for diagnostics and prevention of chronic noninfectious diseases.
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