The problem of carcinogenic risk in offsprings of individuals exposed to radiation is challenging and insufficiently studied. In that there are no evaluations of the interaction between radiation and ...non-radiation factors. The aim of the study was the analysis of interaction of preconceptive radiation exposure and parents' onco-pathology in cancer mortality in offsprings (F1) of workers (fathers) of the Mayak Production Association exposed to a wide range of doses of radiation over a year prior conception. The number of offspring is 8191 individuals (4180 men and 4011 women). The analysis was performed with the use of fourfold table and eightfold tables. The interaction offactors was estimated on the base of the additive and multiplicative models. The studied factors were independent. The odds ratio (OR) of cancer mortality in the offspring with parents' oncopathology (1.43) was insignificant. OR of cancer mortality in preconceptive radiation exposure in a dose over 110 mGy and without parents' onco-pathology was 2.61 (1.52-4.49), and in their combination--3.86 (1.93-7.71). Index of synergism of preconceptive radiation exposure and parents' onco-patholog in the rise of carcinogenic risk in the offspring was 1.34 and the character of their interaction was multiplicative. Thus, for the first time there was established the interaction between radiation and non-radiation factors in the synergism sort in the increase of carcinogenic risk in the offspring of people exposed to radiation.
The role of genetic factors in the development of chronic radiation disease (CRD), mostly caused by occupational external gamma -exposure, was evaluated. The data of molecular genetic survey of a ...cohort of 985 workers at the nuclear power plant, the Mayak PA, were analyzed. Among the genetic markers tested, an association between the haptoglobin (Hp) genetic system and the development of CRD was established. It was demonstrated that the contribution of genetic factors to the CRD onset was realized not within the whole, but in a relatively narrow dose interval (70 to 400 cGy), i.e., was relative. Furthermore, at equal irradiation doses, relatively higher risk of CRD was observed among the Hp 2-2 phenotype carriers (1.96) compared to lower risk among the Hp 1-1 and Hp 2-1 phenotype carriers (0.64). It was shown that with the increase of the irradiation dose, genotypic differences in the CRD frequency decreased to the point of their complete disappearance. Comparison of the roles of the genetic factors in the onset of such deterministic irradiation effect as CRD, with their roles in the onset of lung cancer in tobacco smokers revealed similar patterns. A scheme of the relationships between the effector intensity and the differences in the genetically determined radioresistance is presented. The data obtained do not support the idea that the survivals of the atomic bombing of Hiroshima and Nagasaki were the most radioresistant individuals, who are not representative for evaluating the radiation risk.
The relative center-of-mass energy spread at $e^+e^-$ colliders is about
$10^{-3}$, which is much larger than the widths of narrow resonances produced
in the s-channel in $e^+e^-$ collisions. This ...circumstance greatly lowers the
resonance production rates of J/Psi, Upsilon(1S), Upsilon(2S), Upsilon(3S) and
makes it extremely difficult to observe resonance production of the Higgs
boson. Thus, a significant reduction of the center-of-mass energy spread would
open up great opportunities in the search for new physics in rare decays of
narrow resonances, the search for new narrow states with small
$\Gamma_{e^+e^-}$, the study of true muonium and tauonium, etc. The existing
monochromatization scheme is only suitable for head-on collisions, while
$e^+e^-$ colliders with crossing angles (the so-called Crab Waist collision
scheme) can provide significantly higher luminosity due to reduced collision
effects. In this paper, we propose a new monochromatization method for
colliders with a large crossing angle. The contribution of the beam energy
spread to the spread of the center-of-mass energy is canceled by introducing an
appropriate energy-angle correlation at the interaction point; $\sigma_W/W \sim
(3-5)10^{-6}$ appears possible. Limitations of the proposed method are also
considered.
The application of the two-photon process pp→pp+μ
+μ
− for the luminosity measurements at LHC with the ATLAS detector is considered. The expected accuracy of the absolute offline luminosity ...determination is 1–2% for the luminosity range of 10
33–
10
34
cm
−2
s
−1
. The preliminary cross-section estimates done for LHCb promise the same level of the luminosity measurement accuracy at
L=2×10
32
cm
−2
s
−1
.
Gold-plated processes at photon colliders Boos, E.; De Roeck, A.; Ginzburg, I.F. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
10/2001, Volume:
472, Issue:
1
Journal Article
Peer reviewed
Open access
We review the most important topics and objectives of the physics program of the
γγ,
γe
collider (photon collider) option for an e
+e
− linear collider.
Superconducting technology makes it possible to build a high energy \(e^+e^-\) linear collider with energy recovery (ERLC) and reusable beams. To avoid parasitic collisions inside the linacs, a twin ...(dual) LC is proposed. In this article, I consider the principle scheme of the collider and estimate the achievable luminosity, which is limited by collision effects and available power. Such a collider can operate in a duty cycle (DC) and in a continuous (CW) modes, if sufficient power. With current SC Nb technology (\(T=1.8\) K, \(f_{\rm RF}=1.3\) GHz, used for ILC) and with power \(P= 100\) MW, a luminosity \(L \sim 0.33 \times10^{36}\,\rm cm^{-2}s^{-1}\) is possible at the Higgs factory with \(2E_0=250\) GeV. Using superconductors operating at 4.5 K with high \(Q_0\) values, such as Nb\(_3\)Sn, and \(f_{\rm RF}=0.65\) GHz, the luminosity can reach \(L \sim 1.4 \times10^{36} \,\rm cm^{-2}s^{-1}\) at \(2E_0=250\) GeV (with P=100 MW) and \(L \sim 0.8 \times 10^{36}\,\rm cm^{-2}s^{-1}\) at \(2E_0=500\) GeV (with P=150 MW), which is almost two orders of magnitude greater than at the ILC, where the beams are used only once. This technology requires additional efforts to obtain the required parameters and reliably operation. Such a collider would be the best machine for precision Higgs studies, including the measurement of Higgs self-coupling.
We report results of a search for narrow resonances in e super(+e) super(-) annihilation at center-of-mass energies between 1.85 and 3.1 GeV performed with the KEDR detector at the VEPP-4M e ...super(+e) super(-) collider. The upper limit on the leptonic width of a narrow resonance inline image has been obtained (at 90% C.L.).
PDF
