Thoracic duct drainage (TDD) was performed in 4 patients with severe rheumatoid arthritis. Clinical effects were apparent in all during drainage, but the term of TDD and the cumulative number of ...lymphocytes drained had no direct relation to the improvement of clinical symptoms. The number of lymphocytes in the peripheral blood increased despite discharge of lymphocytes from the thoracic duct in the very early stage of drainage, suggesting that lymph drainage from thoracic duct accelerates migration of lymphocytes from lymphocyte pools to the blood stream. Biopsy specimens of synovial membranes obtained post-TDD showed marked decrease of mononuclear cell infiltration as compared to the specimens obtained preoperatively. These findings suggest that clinical effectiveness may be due not only to systemic immunosuppression induced by lymphocyte depletion but also to accelerated migration of inflammatory cells from the synovial tissues to the blood stream occurring with dynamic change of lymph flow during TDD.
Glaupalol, C15H16O4, isolated from the rhizomes of Glaucidium palmatum Sieb. et Zucc., and its derivatives have been degraded by a variety of methods including ozonolysis and alkaline fusion. ...Chemical and physical evidence of glaupalol, its derivatives, and its degradation products led to the assignment of structure I to glaupalol.
Recurrent dislocation of the elbow Sugita, H; Kotani, H; Ueo, T ...
Nihon geka hokan. Archiv fur japanische Chirurgie,
1994-Sep-01, Volume:
63, Issue:
5
Journal Article
A case of a recurrent dislocation of the elbow joint in a 13-year-old female is described. The patient sustained a medial epicondylar fracture of the humerus and consulted us four months later. There ...was no deformity but marked lateral instability of the elbow was recognized. It could be fully flexed and hyperextended ca 20 degrees. The elbow joint could be easily dislocated by pronation of the hyperextended elbow. Roentgenogram demonstrated an apparent non-union of the medial epicondylar fracture. The fragment was repositioned so that the medial collateral ligament became taut. There was no recurrence of the dislocation ten months postoperatively.
Tazettine was oxidized with chromic acid under the controlled conditions to give a neutral compound, oxotazettine, C18H19O6N·1/2H2O, which was shown to be represented by the formula (II).