A special DC-to-DC converter is designed to supply low-power to the detector system of the J-PARC
g
-
2
/EDM experiment, which aims to measure the anomaly of the muon magnetic dipole moment,
a
μ
=
(
...g
-
2
)
/
2
. The important requirement of the DC-to-DC converter is that the stray magnetic field from the converter should be less than 30
μ
T to reach the experimental sensitivity of 450 ppb. The DC-to-DC converter contains one buck converter and three regulators, featured with a customary designed air-core inductor. The detailed design and test results for the voltage stability, stray magnetic field, and heat dissipation in vacuum are reported.
The J-PARC muon
g
-
2
/EDM experiment aims to measure the muon magnetic moment anomaly
a
μ
=
(
g
-
2
)
/
2
. The target sensitivity for
a
μ
is a statistical uncertainty of
450
×
10
-
9
, and
a
μ
can ...be extracted by measuring the spin precession of muons (
ω
a
). The
ω
a
can be extracted from the distribution of muon decay time, and the time is measured by reconstructing tracks of positrons that are decayed from the muons. To extract
ω
a
precisely, the systematic effects on
ω
a
should be controlled under the aforementioned sensitivity. To study systematic effects, we develop a compact simulation package, and using our developed package, we study several systematic effects and discuss the results. We discuss the implementation details of the package and studies of systematic effects on
ω
a
.
The Belle II experiment is constructed at the KEK High Energy Accelerator Research Organization in Japan. Due to the high luminosity of the beam, a trigger that effectively rejects beam-induced ...background is required. For this purpose, a level-1 trigger board with field-programmable gate arrays and high speed optical transceivers is developed for the central drift chamber trigger readout. Utilizing this hardware, we develop our algorithms, which find segments of charged particle trajectories using information of the central drift chamber.
FDG-PET Imaging in Cervical Cancer Gandy, Nemi; Arshad, Mubarik A.; Park, Won-Ho E. ...
Seminars in nuclear medicine,
November 2019, 2019-11-00, 20191101, Volume:
49, Issue:
6
Journal Article
Peer reviewed
FDG-PET/CT has an established role in the initial staging of locally advanced cervical cancers, particularly in evaluation of nodal disease and distant metastases. It is common practice to perform ...FDG-PET/CT 3 months postcompletion of chemoradiotherapy as it can predict outcome and be used to tailor management, including adjuvant therapy and follow-up. It is also routinely used prior to pelvic exenterative surgery to ensure there is no disease outside the pelvis. There is growing evidence that FDG-PET-derived parameters are prognostic and could potentially be used to tailor therapy. This review outlines the use of FDG-PET/CT imaging in cervical cancer.
Purpose
Cervical cancer metabolic tumour volume (MTV) derived from 18F-FDG PET/CT has a role in prognostication and therapy planning. There is no standard method of outlining MTV on 18F-FDG PET/CT. ...The aim of this study was to assess the optimal method to outline primary cervical tumours on 18F-FDG PET/CT using MRI-derived tumour volumes as the reference standard.
Methods
81 consecutive cervical cancer patients with pre-treatment staging MRI and 18F-FDG PET/CT imaging were included. MRI volumes were compared with different PET segmentation methods. Method 1 measured MTVs at different SUV
max
thresholds ranging from 20 to 60% (MTV
20
-MTV
60
) with bladder masking and manual adjustment when required. Method 2 created an isocontour around the tumour prior to different SUV
max
thresholds being applied. Method 3 used an automated gradient method. Inter-observer agreement of MTV, following manual adjustment when required, was recorded.
Results
For method 1, the MTV
25
and MTV
30
were closest to the MRI volumes for both readers (mean percentage change from MRI volume of 2.9% and 13.4% for MTV
25
and − 13.1% and − 2.0% for MTV
30
for readers 1 and 2). 70% of lesions required manual adjustment at MTV
25
compared with 45% at MTV
30
. There was excellent inter-observer agreement between MTV
30
to MTV
60
(ICC ranged from 0.898–0.976 with narrow 95% confidence intervals (CIs)) and moderate agreement at lower thresholds (ICC estimates of 0.534 and 0.617, respectively for the MTV
20
and MTV
25
with wide 95% CIs). Bladder masking was performed in 86% of cases overall. For method 2, excellent correlation was demonstrated at MTV
25
and MTV
30
(mean % change from MRI volume of −3.9% and − 8.6% for MTV
25
and − 16.9% and 19% for MTV
30
for readers 1 and 2, respectively). This method also demonstrated excellent ICC across all thresholds with no manual adjustment. Method 3 demonstrated excellent ICC of 0.96 (95% CI 0.94–0.97) but had a mean percentage difference from the MRI volume of − 19.1 and − 18.2% for readers 1 and 2, respectively. 21% required manual adjustment for both readers.
Conclusion
MTV
30
provides the optimal correlation with MRI volume taking into consideration the excellent inter-reader agreement and less requirement for manual adjustment.
Abstract
We compute the expected sensitivity on measurements of optical depth to reionization for a ground-based experiment at Teide Observatory. We simulate polarized partial sky maps for the ...GroundBIRD experiment at the frequencies 145 and 220 GHz. We perform fits for the simulated maps with our pixel-based likelihood to extract the optical depth to reionization. The noise levels of polarization maps are estimated as 110
μ
K
arcmin
and 780
μ
K
arcmin
for 145 and 220 GHz, respectively, by assuming a three-year observing campaign and sky coverages of 0.537 for 145 GHz and 0.462 for 220 GHz. Our sensitivities for the optical depth to reionization are found to be
σ
τ
= 0.030 with the simulated GroundBIRD maps, and
σ
τ
= 0.012 by combining with the simulated QUIJOTE maps at 11, 13, 17, 19, 30, and 40 GHz.
The Belle II detector at the SuperKEKB accelerator has a level-1 trigger implemented in field-programmable gate arrays. Due to the high luminosity of the beam, a trigger that effectively rejects ...beam-induced background is required. A three-dimensional tracking algorithm for the level-1 trigger that uses the Belle II central drift chamber detector response is being developed to reduce the recorded beam background while having a high efficiency for physics of interest. In this paper, we describe the three-dimensional track trigger that finds and fits track parameters that we developed.
Microwave kinetic inductance detectors have a variety of potential applications in astronomical observations. We built a data acquisition system for kinetic inductance detectors combining a dedicated ...analog board and a commercially available digital board to meet the requirements of astronomical measurements, such as observation of the cosmic microwave background. This paper reports the status of the development of the data acquisition system. We have already achieved simultaneous readout through 120 channels using a direct down-conversion method to decode the signal. A variety of software has been developed and tested using the functionalities of the system and actual detectors.
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