The link between social class and subjective well-being (SWB) has been an important topic of inquiry, with broad implications for understanding the psychology of social class and the determinants of ...SWB. Prior research on this topic has focused primarily on the extent to which social class affects SWB and the factors that moderate that impact. We extend prior work by examining the concerns that account for why social class shapes SWB. In particular, we examine the role of status and power in mediating the impact of one’s social class on one’s SWB. Across five studies, we theorize and find that status mediates the impact of social class on SWB and, moreover, that status is a stronger mediator of this link than is power. Overall, these studies advance scholarly research on the psychology of social hierarchy by clarifying the interplay between social class, status, and power in relation to SWB.
Urban plans often ignore the uneven impacts of hazards on socially vulnerable populations. We evaluate the degree to which equity policies in local networks of plans support risk reduction for ...socially vulnerable populations, and examine the relationship between equity policies scores and the level of social vulnerability in six cities exposed to floods and projected sea level rise. We find high variability in equity policy support for risk reduction, and that equity policies in plans actually actively increase risk of loss in neighborhoods with high levels of social vulnerability, which in turn could disrupt further development.
Hierarchies take different forms, which individuals mentally represent using different geometric shapes. We propose and empirically demonstrate that individuals’ mental representations of the shape ...hierarchy takes affect its consequences. Five studies compared two common mental representations of hierarchy shapes—ladders and pyramids—to explore whether, why, and how individuals’ perceptions of hierarchy’s shape undermine constructive relationships within groups and group performance. Study 1 demonstrated that individuals commonly mentally represent hierarchies as ladders and pyramids. In Studies 2 and 3, employees who perceived their workplace hierarchies to be shaped like ladders (as compared with pyramids) experienced worse intragroup relationships. Finally, Studies 4 and 5 experimentally manipulated groups’ hierarchical shape in the lab and found that ladder-shaped hierarchies undermined social relationships and group performance relative to pyramid-shaped hierarchies. Taken together, these findings enhance our understanding of hierarchies’ multifaceted consequences and help shed light on the (dis)utility of hierarchy for group functioning.
The tumor suppressor p53 is the central hub of a molecular network, which controls cell proliferation and death, and also plays an important role in the occurrence and development of liver fibrosis. ...The abundant post-translational processing and modification endow the functional diversity of p53. Considering the relationship between p53 and liver fibrosis, drug intervention targeting p53 or management of p53 regulation might be effective strategies to treat liver fibrosis. Here, we systematically discuss the regulation of p53 in different liver cells (hepatocytes, immune cells, HSCs,
etc
) and the role of p53 in the development of liver fibrosis, and propose possible interventions to prevent the pathogenic processes of liver fibrosis.
With the rapid development of the Internet-of-Things (IoT), a massive amount of transient data is transmitted in edge networks. Transient data are highly time-sensitive, such as monitoring data ...generated by industrial devices. Due to their inefficiency, traditional caching strategies in edge networks are inadequate for handling transient data. Thus, to improve the efficiency of transient data caching, we construct a freshness model of transient data and propose a maximum entropy Actor–Critic-based caching strategy, TD-MEAC-which can improve the freshness of cached data and reduce the long-term caching cost. Simulation results show that the proposed TD-MEAC achieves a higher cache hit rate and maintains a higher average freshness of cached transient data compared with the existing DRL and baseline caching strategies.
In the experiments reported here, we integrated work on hierarchy, culture, and the enforcement of group cooperation by examining patterns of punishment. Studies in Western contexts have shown that ...having high status can temper acts of dominance, suggesting that high status may decrease punishment by the powerful. We predicted that high status would have the opposite effect in Asian cultures because vertical collectivism permits the use of dominance to reinforce the existing hierarchical order. Across two experiments, having high status decreased punishment by American participants but increased punishment by Chinese and Indian participants. Moreover, within each culture, the effect of status on punishment was mediated by feelings of being respected. A final experiment found differential effects of status on punishment imposed by Asian Americans depending on whether their Asian or American identity was activated. Analyzing enforcement through the lens of hierarchy and culture adds insight into the vexing puzzle of when and why people engage in punishment.
Fructose, especially industrial fructose (sucrose and high fructose corn syrup) is commonly used in all kinds of beverages and processed foods. Liver is the primary organ for fructose metabolism, ...recent studies suggest that excessive fructose intake is a driving force in non-alcoholic fatty liver disease (NAFLD). Dietary fructose metabolism begins at the intestine, along with its metabolites, may influence gut barrier and microbiota community, and contribute to increased nutrient absorption and lipogenic substrates overflow to the liver. Overwhelming fructose and the gut microbiota-derived fructose metabolites (e.g., acetate, butyric acid, butyrate and propionate) trigger the
de novo
lipogenesis in the liver, and result in lipid accumulation and hepatic steatosis. Fructose also reprograms the metabolic phenotype of liver cells (hepatocytes, macrophages, NK cells, etc.), and induces the occurrence of inflammation in the liver. Besides, there is endogenous fructose production that expands the fructose pool. Considering the close association of fructose metabolism and NAFLD, the drug development that focuses on blocking the absorption and metabolism of fructose might be promising strategies for NAFLD. Here we provide a systematic discussion of the underlying mechanisms of dietary fructose in contributing to the development and progression of NAFLD, and suggest the possible targets to prevent the pathogenetic process.
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