Synopsis
Little is known as the effects of mobile connected dermatoscope services on diagnostic accuracy for sensitive skin. Confocal laser scanning microscope (CLSM) can non‐invasively measure the ...thickness of epidermis. Combination of the two devices to observe sensitive skin may receive unexpected effects. To evaluate the application effect on sensitive skin with the combination of Handyscope and confocal laser scanning microscope. Twenty simple sensitive‐skinned patients and 20 volunteers participated in the study. Cheek, typically, dermoscopic images were obtained from patients, and the changes in the skin texture were observed. Their epidermis thicknesses as well as the volunteers’ were measured so that the thicknesses of the two groups were compared. Dermoscopic pictures of the skin texture obviously showed that dilated capillaries looked like earthworms with pigmented patches more or less floating above, and skin roughness as well as deepened dermatoglyph were also conspicuously present in some patients. The mean epidermal thickness of the patients was 79.01 μm and the volunteers’ was 85.78 μm. The difference between the two groups reached 6.77 μm. There was a statistical significance (P = 0.001). Mobile connected dermatoscope and confocal laser scanning microscope might be the choice for simple sensitive skin investigation.
Résumé
On connait peu l’impact de l’utilisation des dermatoscopes mobiles connectés en ligne sur la précision du diagnostic des peaux sensibles. Le microscope confocal à balayage laser (CLSM) peut, de manière non‐invasive, mesurer l’épaisseur de l’épiderme.La combinaison des deux dispositifs permettant d’observer la peau sensible peut révéler des effets inattendus. évaluer l’effet de l’utilisation conjointe du Handyscope™ et du microscope confocal à balayage laser pour observer les peaux sensibles. 20 patients à peaux sensibles et 20 volontaires témoin ont participéà l’étude. Des images dermoscopiques des joues ont été obtenues chez des patients et les changements de la texture de la peau ont été observés. L’épaisseur de l’épiderme a été mesurée dans les deux groupes pour comparaison. Les images dermoscopiques des peaux sensibles montrent des capillaires dilatées, avec des taches pigmentées, de la rugosité augmentée et des dermatoglyphes plus profonds chez certains patients. L’épaisseur moyenne épidermique des patients était de 79.01 μm, celle des volontaires était 85.78 μm, la différence entre les deux groupes de 6.77 μm étant statistiquement significatif (p <0.001). Le dermatoscope mobile connecté et le microscope confocal à balayage laser pourrait être la méthode de choix pour caractériser la peau sensible.
The aim of this study was to estimate, among college students ages 18-24, the numbers of alcohol-related unintentional injury deaths and other problems over the period from 1998 through 2005.
The ...analysis integrated data on 18- to 24-year-olds and college students from each of the following data sources: the National Highway Traffic Safety Administration Fatality Analysis Reporting System, Centers for Disease Control and Prevention Injury Mortality Data, National Coroner Studies, census and college enrollment data, the National Household Survey on Drug Use and Health, and the College Alcohol Study.
Among college students ages 18-24, alcohol-related unintentional injury deaths increased 3% per 100,000 from 1,440 in 1998 to 1,825 in 2005. From 1999 to 2005, the proportions of college students ages 18-24 who reported consuming five or more drinks on at least one occasion in the past month increased from 41.7% to 44.7%, and the proportions who drove under the influence of alcohol in the past year increased from 26.5% to 28.9%-7% and 9% proportional increases, respectively. The increases occurred among college students ages 21-24, not 18-20. In 2001, 599,000 (10.5%) full-time 4-year college students were injured because of drinking, 696,000 (12%) were hit or assaulted by another drinking college student, and 97,000 (2%) were victims of alcohol-related sexual assault or date rape. A 2005 follow-up of students in schools with the highest proportions of heavy drinkers found no significant changes in the proportions experiencing these events.
The persistence of college drinking problems underscores an urgent need to implement prevention and counseling approaches identified through research to reduce alcohol-related harms among college students and other young adults.
The aim of this study was to assess if the entire mediastinum (M), the bilateral supraclavicular area (S), and the left gastric area (L) should be all included in the irradiation volume. The clinical ...data of 204 patients with thoracic esophageal squamous cell carcinoma who had undergone prophylactic postoperative radiotherapy after radical surgery were retrospectively reviewed. They were classified into four groups: group A, 26 patients with irradiated M alone; group B, 139 patients with irradiated M + S; group C, 10 patients with irradiated M + L; and group D, 29 patients whith irradiated M + S + L. The 5‐year disease‐free survival rates were 36% in group A, 31% in group B, 40% in group C and 44% in group D (χ2=3.05, P =0.39), respectively. Multivariate analysis revealed that the irradiated extent was not a significant influential factor (hazard ratio=0.84, 95% confidence interval, 0.69–1.03, P =0.10). None of 43 patients without the L irradiated and with disease in the upper and middle upper thirds (defined in middle third but with upper third invaded), and one of 83 patients without the L irradiated and with disease in the middle third only thoracic esophagus were shown to have abdominal lymph node metastasis. Supraclavicular lymph node metastasis in patients in the lower and middle lower thirds (defined in middle third but with lower third invaded) were, respectively, 1/43 and 1/18 whether the S was irradiated or not. It seems unnecessary that the L be irradiated when the primary site is in the upper, middle, and middle upper thirds of the thoracic esophagus after radical surgery. Similarly, S may be unnecessarily irradiated in the lower and middle lower thirds.
This paper presents the design of a companding nonuniform optimal scalar quantizer for speech coding. The quantizer is designed using two neural networks to perform the nonlinear transformation. ...These neural networks are used in the front and back ends of a uniform quantizer. Two approaches are presented in this paper namely adaptive critic designs and particle swarm optimization, aiming to maximize the signal-to-noise ratio. The comparison of these optimal quantizer designs over a bit-rate range of 3-6 is presented. The perceptual quality of the coding is evaluated by the International Telecommunication Union's Perceptual Evaluation of Speech Quality standard
A series of experiments has recently been carried out in EAST under different plasma conditions to investigate the basic divertor performance, divertor and SOL screening efficiency and radiative ...divertor effect. Detached divertor plasmas have been achieved by density ramp-up. It is found that CIII emission from the low-field side (LFS) exhibits a strong dependence on poloidal locations and plasma operation regimes from methane (CH4) puffing experiments. In addition, the radiative divertor experiments by injection of mixed Ar (5.7% Ar in D2) into the outer divertor chamber reduce the peak heat flux by 50% at the outer target plate, which also reduce the divertor plasma temperature. The in–out heat flux distribution asymmetry is improved.
Effect of sublethal exposure to chlordecone on life history characteristics of freshwater rotifer Brachionus calyciflorus pallas was examined. Chlordecone at 0.5 and 50 mu g/L prolonged the ...generation time, which contributed to the prolonged duration of the juvenile period. Chlordecone at 50 mu g/L prolonged the reproductive period and the mean life span. Chlordecone at 0.5 to 50 mu g/L increased the lifetime egg production and the net reproduction rate. Chlordecone at 0.0005 to 50 mu g/L did not significantly influence the intrinsic rate of population increase or the life expectancy at hatching of the rotifers, indicating that chlordecone at 0.0005 to 50 mu g/L would not induce any significant effects on the growth of the natural B. calyciflorus population.
The organochlorine insecticide aldrin is commonly used in intensive agriculture, and demonstrates estrogenic activity. Rotifers such as Brachionus calyciflorus are favored test animals in aquatic ...toxicology because of their more sensitivity to most toxicants. In the tested concentration range of 0.04-1.28 mg/L, aldrin shortened significantly the durations of embryonic development. Lower concentrations of aldrin had an intriguing effect on the reproduction of the rotifers and are beneficial to their survival. Different endpoints of both development and reproduction had different sensitivity to aldrin. The reproductive endpoint of the rotifers is more sensitive to aldrin than the developmental endpoint.
The ATP-binding cassette (ABC) transporters belong to a large superfamily of proteins that have important physiological functions in all living organisms. In insects, ABC transporters have important ...functions in the transport of molecules, and are also involved in insecticide resistance, metabolism, and development. In this study, the Nilaparvata lugens Stal (Hemiptera: Delphacidae) ABCG (NlABCG) gene was identified and characterized. The complete mRNA sequence of NlABCG was 2608-bp long, with an open reading frame of 2064 bp encoding a protein comprised of 687 amino acids. The conserved regions include three N-glycosylation and 34 phosphorylation sites, as well as seven transmembrane domains. The amino acid identity with the closely related species Acyrthosiphon pisum was 42.8%. Developmental expression analysis using quantitative real-time reverse transcriptase PCR suggested that the NlABCG transcript was expressed at all developmental stages of N. lugens. The lowest expression of NlABCG was in the 1st instar, and levels increased with larval growth. The transcript profiles of NlABCG were analyzed in various tissues from a 5th instar nymph, and the highest expression was observed in the midgut. These results suggest that the sequence, characteristics, and expression of NlABCG are highly conserved, and basic information is provided for its functional analysis.
Abstract Synovial chondromatosis is a rare benign arthropathy characterized by chondrometaplasia of the synovial membrane, particularly in the temporomandibular joint (TMJ). The purpose of this ...article is to describe an uncommon case of synovial chondromatosis arising from the inferior joint space of the TMJ with an enlarged condyle secondary to preauricular trauma in a 44-year-old healthy male. The possible role of a traumatic event in the etiology, the usefulness of the combined performance of CT and MRI examinations for preoperative diagnosis and current treatment are discussed.
We report the measurements by the STAR Collaboration of J/ψ invariant yields as a function of transverse momentum at mid-rapidity (|y|<1.0) in p+p collisions at s=500 GeV, in Au+Au collisions at ...sNN=39, 62.4 and 200 GeV, and in U+U collisions at sNN=193 GeV. The centrality, beam energy and collision system dependences of J/ψ production and nuclear modification factors are discussed. We also report the ratio of ψ(2S) to J/ψ yields in p+p collisions at s=500 GeV and ϒ production in U+U collisions at sNN=193 GeV.
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