L. contains more than 100 phytocannabinoids that can interact with cannabinoid receptors CB
and CB
. None of the cannabinoid receptor ligands is entirely CB
- or CB
-specific. The effects of ...cannabinoids therefore differ not just because of different potency at cannabinoid receptors but also because they can interact with other non-CB
and non-CB
targets, such as TRPV1, GPR55, and GPR119. The most studied phytocannabinoid is Δ
-tetrahydrocannabinol (THC). THC is a partial agonist at both cannabinoid receptors, but its psychotomimetic effect is produced primarily via activation of the CB
receptor, which is strongly expressed in the central nervous system, with the noteworthy exception of the brain stem. Although acute cognitive and other effects of THC are well known, the risk of irreversible neuropsychological effects of THC needs further research to elucidate the association. Unlike THC, phytocannabinoid cannabidiol (CBD) does not appear to have psychotomimetic effects but may interact with some of the effects of THC if taken concomitantly. CBD administered orally has recently undergone well-controlled clinical trials to assess its safety in the treatment of paediatric epilepsy syndromes. Their findings point to increased transaminase levels as a safety issue that calls for postmarketing surveillance for liver toxicity. The aim of this review is to summarise what is known about acute and chronic toxicological effects of both compounds and address the gaps in knowledge about the safety of exogenous cannabinoids that are still open.
V članku se avtorica osredotoča na urbane študije na področju rudarstva. Pojasni načine antropološke vpetosti države, mednarodnih korporacij in avtohtonih skupnosti v polje rudarstva ter ...pojasni antropološko vlogo v diskurzih. V drugem delu članka se posveča skupinam, ki so le posredno povezane z rudarsko industrijo. Na tem mestu pokaže po- membnost antropološke pozornosti tudi tam, kjer vplivi rudarske industrije niso očitni.
The paper presents the findings of the first large-scale survey on post-mortem organ donation among the general Slovenian population. It focuses on the reported donation willingness, the barriers to ...joining the register of organ donors and the position towards consent to donate organs of deceased relatives.
A face-to-face survey was conducted on a probability sample of 1,076 Slovenian residents between October and December 2017. The performed analyses included estimations of means and proportions for target variables, an evaluation of between-group differences and a partial proportional odds model to study the relations between organ donation willingness and socio-demographic characteristics.
The mean reported willingness to donate one's own organs after death was 3.77 on a 5-point scale, with less than a third of respondents claiming to be certainly willing. Only 6% of those at least tentatively willing to donate organs were certain to join the register of organ donors in the future. The most frequently reported barriers to registration were unfamiliarity with the procedure and a lack of considering it beforehand. The reported willingness to donate organs of a deceased relative strongly depended on the knowledge of the relative's wishes, yet 80% of the respondents did not discuss their wishes with any family members.
The findings confirm the gap between the reported donation willingness and joining the register of donors. Future post-mortem organ donation strategies need to consider socio-demographic and attitudinal factors of donation willingness and help stimulate the communication about organ donation wishes between family members.
In this book (' The Spaces of Slovenian Literature'), a team of researchers from the ZRC SAZU and the Faculty of Arts in Ljubljana led by Marko Juvan develops a new discipline, which is formed at the ...intersection between the analysis of the literary system and geography and relies on geographic information systems. Based on the spatial humanities approach presented in the introductory chapters, the following analyses, thematic maps and graphs try to explain how the “national space” was formed both ideologically and materially due to the interaction between geographical factors and literary practices in Slovenian from 1780 to 1940. The argument is based on spatial statistical analysis of data sets of biographies of literary actors, development of the press, publishing, literary clubs and theaters, the places represented in historical novels, and a constellation of memorial objects and designations dedicated to Slovenian writers. Systemic treatment is supplemented with discussions on the depicted and living spaces of selected writers from the 17th to the 21st century.
Prispevek se loteva aktualnega in problemskega vprašanja opredelitve povedkovnika in opozarja na različne tipe biti-stavkov. Je poskus analize in sopostavitve stavkov z zloženim povedkom, ki v ...slovenščini in ruščini označujejo trenutno in aktualno stanje.
Članek obravnava Plavtovo komedijo Rudens; izhaja iz prologa, ki v komedijo z izpostavljanjem izrazito rimskih pojmov pietas in fides vnaša resnoben didaktično-moralizirajoč ton; posveča se analizi ...omenjenih pojmov, pri tem pa se dotika vprašanj, ki zadevajo komično konvencijo in komedijo kot dramsko zvrst nasploh.
The monograph is a translated and complemented edition of the book Airborne laser scanning raster data visualization: A Guide to Good Practice. It provides an insight into a range of visualization ...techniques for high-resolution digital elevation models (DEMs). It is provided in the context of investigation and interpretation of various types of historical and modern, cultural and natural small-scale relief features and landscape structures. It also provides concise guidance for selecting the best techniques when looking at a specific type of landscape and/or looking for particular kinds of forms.The three main sections – descriptions of visualization techniques, guidance for selection of the techniques, and visualization tools – accompany examples of visualizations, exemplar archaeological and geomorphological case studies, a glossary of terms, and a list of references and recommendations for further reading. The structure facilitates people of different academic background and level of expertise to understand different visualizations, how to read them, how to manipulate the settings in a calculation, and choose the best suited for the purpose of the intended investigation.
Provider: - Institution: - Data provided by Europeana Collections- Časopis za zabavo, znanost in umetnost je izhajal mesečno v Mariboru. Vseboval je prilogo: Vestnik. Pri urejanju so sodelovali Janko ...Pajk, Davorin Trstenjak in Josip Jurčič- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Časopis za zabavo, znanost in umetnost je izhajal mesečno v Mariboru. Vseboval je prilogo: Vestnik. Pri urejanju so sodelovali Janko ...Pajk, Davorin Trstenjak in Josip Jurčič- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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