Small heat shock proteins (sHsps) are molecular chaperones of low molecular weight involved in an early association with misfolded proteins. In response to heat shock, B. emersonii induces the ...synthesis of a number of proteins. As sHsps are still poorly studied in B. emersonii and in fungi overall, the aim of this work was to carry out a in-depth characterization of sHsps during B. emersonni life cycle, as well as in response to thermal stress. We verified a strong induction of the hsp17 gene in cells exposed to heat shock both in germination and sporulation stages, and that Hsp17 protein levels show the same pattern of variation of its mRNA. Unlike hsp17 and hsp30, hsp16 gene is not significantly induced during heat shock, in germination or sporulation cells. However, at normal temperatures, the hsp16 gene presents high mRNA levels in sporulation cells, whereas the hsp30 gene presents high mRNA levels in germination cells. Interestingly, heat shock mRNA levels for hsp17 and hsp30 genes are 10 times higher in germination cells than in sporulation cells. Thus, our data show that the expression of these sHsp genes is quite distinct, both under normal temperature as during heat shock.
Today, the issue of the physical and psychological safety of residents of residential buildings and their impact on the environment are major concerns for residents, builders, and sellers of the ...construction industry. The design and construction with the Health Safety, Environmental (HSE) approach can influence the direct and indirect costs of the construction industry and is considered an important criterion for pricing at a time of sell. Creating models that can demonstrate the degree of adherence of a building to safety, health, and environmental standards can be effective in the usage as well as the physical and mental comfort of residents using that building. Accordingly, the purpose of this research is to provide a conceptual model for determining the performance criteria of buildings with the HSE approach. This study was carried out based on the practical purpose of the research as well as on a descriptive-analytic method. In this study, the factors affecting HSE performance were first determined. Then, Decision-Making Trial and Evaluation Laboratory (DEMATEL) method was used in a fuzzy environment to measure cause and effect relationships. The findings of the research suggested that among the factors affecting building performance, the safety of the structure is the most influential factor, and the architectural welfare is the most important factor, which itself is in the category of influential factors and is affected by other factors. Creating structures that can assess the performance of a building with the Health Safety, Environmental (HSE) approach can be an important criterion in making decision at the time of designing, constructing, operating, purchasing, and housing for customers and residents of a building. This issue can be considered an indicator in the construction process. Government agencies, the insurer, and price-setting agent of buildings can also use this model for valuation and rank buildings and defining their premium rates.
The evolution of a safe‐by‐design work premised on nanotechnology relies on the regulation of healthcare, safety, and environmental concerns throughout the manufacture, handling, preservation, ...assimilation, and disposal of nanomaterials. The practically infinite potential for nanoparticles to be functionalized, chemically interacted with, and added to new products necessitates a new management method for the safe and hazard‐free application of nanotechnology. Nanomaterials (NMs) like silver NMs and nanomaterial composites have a limited quantity of accurate toxicity and ecotoxicological evidence, which has a severe effect on the ecosystem. Due to the intricate and cross‐disciplinary architecture for several components and processes at the nanoscale, risk assessment in the field of nanotechnology necessitates an integrated interdisciplinary approach. In this review, the study begins by providing an insight into the general characteristics of nanoparticle synthesis and ecotoxicity assessments using a variety of green solutions. In addition, there are sections on safety protocols that encourage industrialists to use NMs more effectively in their operations.
The establishment of smart construction sites employing smart technologies for real-time interconnection, communication, and interaction has emerged as an interesting topic for researchers and ...practitioners in the architecture, engineering, and construction industry as they contribute to effective, efficient, and high-quality on-site management. However, little consideration has been involved in the comprehensive management of health, safety, and environment (HSE) issues using smart technologies. To address this gap, this study first performs a systematic procedure to identify the articles (results = 325) associated with the on-site application of smart technologies for HSE and conducts a quantitative and qualitative analysis on their research trend and interests. A bibliometric analysis of publication numbers by year, country and region, and journal presents the research state quo and trends, and a keyword co-occurrence analysis is conducted to show the interests of this topic. Based on these interests, different smart technologies including techniques and devices are categorized for on-site HSE management objectives. Moreover, a comprehensive framework for smart technologies in HSE management and a blueprint for HSE-oriented smart construction site establishment are put forward. This study develops a basis to understand the current application of smart technologies in HSE management and contributes to the implementation of smart construction sites for sustainable construction.
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•Research trend and interests of smart technologies for on-site HSE are analyzed.•Related smart technologies are discussed according to various management objectives.•A framework consisting of smart technologies and application fields is developed.•A blueprint for HSE-oriented smart construction site establishment is put forward.
Nowadays, the change and dynamism of organizations are the basic principles; therefore, managers should modify the goals, plans and work procedures so that they can be compatible with the environment ...condition. The management of HSE is not excepted from this principle. The aim of this study was to evaluate the processes affecting HSE. This study was a cross-sectional and applied study using the review of relevant documentation, interviews and brainstorming with experts, and the reviews of Best Practice to identify the HSE's processes. After checking the HSE activities, the 5 processes of HSE training, managing the risks, events, emergencies and contractors and any changes in the other processes of the organization were also suggested. The results showed that a process approaching the form of an intervention programed can be provided in order to have a better interaction between the HSE activities and organizations processes and workplace health promotion for the HSE activities.
This study tackled the global challenge of managing specialized hospital waste, emphasizing its sensitivity due to toxic and pathogenic agents. Focused on Imam Khomeini Hospital (RA), the research ...employed both quantitative and qualitative approaches to assess waste production, evaluating health, safety, and environmental risks. Over a 3-month period, sampling at the hospital waste station covered household, infectious, medicinal, and sharps waste. Results disclosed an average per capita healthcare waste production of 3.52 kg per bed per day, with specific breakdowns for various waste types. The study evaluated waste management quality, establishing acceptable conditions. Utilizing the Failure Mode and Effects Analysis (FMEA) technique, health, safety, and environment risk assessments identified potential risks in different waste management sectors. Comparisons with global studies and national average levels highlight elevated per capita hospital waste production in Urmia city, necessitating increased attention to align facilities with World Health Organization (WHO) standards. The study emphasizes the importance of allocating funds, providing training, raising awareness, and implementing effective waste management methods to address identified challenges, underscoring the need for clear organizational structures and decision-making authorities in hospital waste control aligned with international standards.
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Doubtlessly, noting the growth of industry and the criticality of the environment at the present time and the significance of protecting and preserving the resources to achieve the sustainable ...development, establishing the appropriate cultural mechanisms which can be able to confront the probable problems rationally besides understanding the biological and human resources for achieving the goals of sustainable development and establish matching with the conditions is so necessary. Today, the subject of HSE in the industry and creating its relevant cultural context in the developing countries is significant and it is necessary to assess its position at the organizational level in several sessions. Assessing the climate of HSE in an organization can depict a realistic picture of the staff understanding of the subject of HSE and their duties. The purpose of carrying out this study is to identify the main assessing factors of the climate of HSE in an organization and studying one of the industrial units in order to determine the position of them with a view to HSE. This descriptive-analytical study is being carried out based on the review of the literature and its results to identify the factors of HSE climate and then assessing the climate of HSE among the staff of a combined cycle power plant. The survey (questionnaire) contains forty-three questions and is adjusted based on the 9- point Likert Scale Eight factors are being determined by means of an appropriate correlation for assessing the HSE climate. The validity of the questionnaire was achieved by means of Cronbach’s Alpha coefficient of 0.727 and the final result of the questionnaire evaluates an intermediate climate of HSE in the organization.
Background and aims: Assessment of performance indicator is one of the most important issues in the managerial systems that should be done in a correct way. The accuracy of the assessment is ...influenced by the assessorschr('39') judgment. This study was done in order to determine pattern of assessing of HSE unit performance in the steel industries. Methods: In this study, 7 experts were defined indicators for assessing the performance of HSE units in the steel industry. Then, the weights of the indicators were obtained by fuzzy linguistic terms. Then, one of the largest steel industries was assessed by using normalized weights of the indicators. Results: the results of this study showed, that the most important index in Health domain is occupational disease control program (0.057) and the most important index in safety domain is fire hazard control program (0.062) and in Environmental domain was air pollution control program (0.054). Also, the results showed that the most common causes of reduced HSE unit performance were related to health and environment domains indices. Conclusion: Results showed that the majority of safety indicators were influenced by HSE Managerial Systems in the short term; however, this system needs more time to show its efficacy in the Health and Environmental domains indicators.
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