Vulval malignancies per se are very rare and a liposarcoma in this location is rarer still. The literature consists only of case reports of patients, often with a very limited follow up. We present a ...rare case of a young 30 year old unmarried nulliparous woman presenting with a giant vulval mass of 30*20 cm and weighing nearly 6 kilograms. Ultrasonography, Computed Tomography, Magnetic Resonance Imaging and biopsy were done. Local resection with adjuvant radiotherapy was given. Histopathology was suggestive of myxoid liposarcoma and the patient is presently recurrence free with over 8 years of follow up. Though rare, myxoid liposarcoma should be kept in differential diagnosis of vulval soft tissue mass. Management includes a combination of surgery and radiation. Excision of lymph nodes is not recommended. Strict prolonged follow up for recurrence or metastasis is mandatory, and any new complaints should be addressed promptly. This is particularly true in the setting of liposarcoma, which may exhibit unusual patterns of spread and recurrence. Keywords: Myxoid liposarcoma, Vulvar mass, Vulvar tumor, Giant mass, Case report
A case benign struma ovarii Paul, P.G; Annal, Anjana; Chowdary, K. Anusha ...
International Journal of Reproduction, Contraception, Obstetrics and Gynecology,
03/2021, Volume:
10, Issue:
3
Journal Article
Open access
Struma ovarii is a rare ovarian tumor and a monodermal variant of dermoid tumors of the ovary in which thyroid tissue components constitute more than 50% of the mass. Struma ovarii accounts for ...0.5-1.0% of all ovarian tumors and 2-5% of ovarian teratomas. Most cases are benign, but malignant transformation is found in a small percentage. It usually presents as a unilateral adnexal mass at fifth and sixth decades of life, with symptoms like other ovarian tumors. The definitive diagnosis is made by histological examination. Adnexectomy remains the standard line of treatment for benign disease. A 41-year-old lady presented with pain in abdomen for 3 months. On ultrasonography and MRI, a multiloculated solid cystic lesion of 7*6 cm with internal echoes was found in the right adnexa. Laparoscopic right adnexectomy was performed. Histopathology was consistent with struma ovarii. Due to its vague clinical manifestations and diverse imaging characteristics, pre-operative diagnosis is challenging. Keywords: Struma ovarii, Ovarian thyroid, Adnexectomy
Background: This study aimed to know the various histo-pathological patterns of endometrial biopsy and their incidence in patients of AUB. Methods: Patients in the age group between 21-75 years who ...had presented with AUB and underwent endometrial biopsy from 1st January 2017 to 31st December 2019 were included. The endometrial biopsy specimens which were already taken from patients with AUB were scrutinized for histopathological pattern. Various patterns of histopathology of endometrial biopsy were noted and studied. Results: Most common age group which was affected was between 36-40 years. The endometrial biopsies and curetting's on histopathology revealed various patterns ranging from normal endometrium to malignancy. Patterns of normal cyclical endometrium (proliferative and secretory phases) were the most common patterns. Conclusions: Evaluation of women with AUB is important around the perimenopausal age group to detect any atypical and malignant changes and intervene early. Histopathological examination in correlation to radiological findings remain the standard procedures for diagnosis. Keywords: AUB, Endometrial biopsy, Malignancy
A novel chitosan-gammaPGA polyelectrolyte complex hydrogel (C-PGA) has been developed and proven to be an effective dressing for wound healing. The purpose of this study was to evaluate if C-PGA ...could promote new bone formation in the alveolar socket following tooth extraction. An animal model was proposed using radiography and histomorphology simultaneously to analyze the symmetrical sections of Wistar rats. The upper incisors of Wistar rats were extracted and the extraction sockets were randomly treated with gelatin sponge, neat chitosan, C-PGA, or received no treatment. The extraction sockets of selected rats from each group were evaluated at 1, 2, 4, or 6 wk post-extraction. The results of radiography and histopathology indicated that the extraction sockets treated with C-PGA exhibited lamellar bone formation (6.5%) as early as 2 wk after the extraction was performed. Moreover, the degree of new bone formation was significantly higher (P 0.05) in the extraction sockets treated with C-PGA at 6 wk post-extraction than that in the other study groups. In this study, we demonstrated that the proposed animal model involving symmetrical sections and simultaneous radiography and histomorphology evaluation is feasible. We also conclude that the novel C-PGA has great potential for new bone formation in the alveolar socket following tooth extraction.
The histology and histochemistry of the adrenal gland of the African giant rat, AGR (Cricetomys gambianus Waterhouse) was carried out using ten adult male rats with the knowledge of providing ...information which could be helpful in an improved knowledge of the structure and function of the gland. The adrenal gland of the African giant rat has a distinct cortex and medulla surrounded by a thin rim of capsule. The adrenal cortex has three zones which are basically the zona glomerulosa, zona fasiculata and zona reticularis with the absence of zona intermedia. The zona glomerulosa contains polyhedral cells which form irregular clusters or cords while the zona fasiculata had radial cells of cuboidal or polyhedral shape. The cells of zona reticularis are similar to those of the zona fasiculata and in addition contain small cells as irregular cords and clusters. The cells of the adrenal medulla are composed of irregular epithelioid cells arranged in rounded groups or short cords and are mostly columnar or polyhedral chromaffin cells which are separated by sinusoids. The adrenal capsule, cortex and medulla were Periodic Acid-Schiff-positive.The adrenal capsule and adrenal medulla was Masson Trichrome-positive unlike the zona fasiculata and zona reticularis. The adrenal capsule and zona glomerulosa were Verhoeff-positive unlike the other zones of the gland. In conclusion the histology of the adrenal gland of the AGR is similar to those of other mammals with a few exceptions, the entire gland is rich in carbohydrate while the capsule and by extension, the outermost portion of the cortex are rich in collagen and elastic fibers. The outcome of this research provides information needed in the better improved understanding of the structure and function of the adrenal gland of the animal. KEY WORDS: Adrenal Gland; African Giant Rat; Cortex; Medulla. La histologia y la histoquimica de la glandula suprarrenal de la rata africana gigante (Cricetomys gambianus Waterhouse) (RGA) se llevo a cabo utilizando diez ratas macho adultas con el objetivo de proporcionar informacion que podria ser util para un mejor conocimiento de la estructura y funcion de la glandula. La glandula suprarrenal de la rata africana gigante tiene una corteza y una medula distintas, rodeadas por un borde delgado de la capsula. La corteza suprarrenal tiene tres zonas que son basicamente: zona glomerulosa, zona fasciculata y zona reticular, con ausencia de zona intermedia. La zona glomerulosa contiene celulas poliedricas que forman racimos irregulares o cuerdas, mientras que la zona fasciculata tenia celulas radiales de forma cuboidal o poliedrica. Las celulas de la zona reticular son similares a las de la zona fasciculata y ademas contienen celulas pequenas como cordones irregulares y racimos. Las celulas de la medula suprarrenal estan compuestas por celulas epitelioides irregulares dispuestas en grupos redondeados o cuerdas cortas y son en su mayoria celulas cromafines columnares o poliedricas, que estan separadas por sinusoides. La capsula suprarrenal y la medula suprarrenal fueron positivas con tricromico de Masson, a diferencia de la zona fasciculata y la zona reticular. La capsula suprarrenal y la zona glomerulosa fueron positivas a Verhoeff, a diferencia de las otras zonas de la glandula. En conclusion, la histologia de la glandula suprarrenal de la RGA es similar a la de otros mamiferos con algunas excepciones; toda la glandula es rica en carbohidratos, mientras que la capsula y por extension, la parte mas externa de la corteza, son ricas en colageno y fibras elasticas. El resultado de esta investigacion proporciona informacion necesaria para mejorar la comprension de la estructura y funcion de la glandula suprarrenal del animal. PALABRAS CLAVE: Glandula suprarrenal; Rata africana gigante; Corteza; Medula.
The goal of this study was to perform a comparative analysis of the microstructure and secretion of the parotid and mandibular glands of adult female lowland tapir and aardvark. Histological and ...histochemical analyses showed that while the parotid gland of the lowland tapir consists of numerous large lobes of different shapes, those of the aardvark were smaller and more ovoid in shape. The parotid gland lobes were of different sizes (small, medium, and large) and shapes in the tapir, while all were roughly ovoid in shape in the aardvark. The obtained results showed that the mandibular gland secretion had a mucoserous character in aardvark, while in lowland tapir, the dominance of mucous secretion was determined. These differences could be related to the specific diets of these two different species. In terrestrial mammals, the parotid and mandibular glands secrete different types of saliva into the oral cavity. Both glands were obtained from two female lowland tapirs (Tapirus terrestris) and one female aardvark (Orycteropus afer) from the Wroclaw Zoological Garden (Poland) and examined by light microscopy (hematoxylin and eosin, mucicarmine, periodic acid-Schiff, Alcian blue pH 1.0, Alcian blue pH 2.5, Alcian blue pH 2.5/PAS, and Hale's dialysed iron). Both the parotid glands observed in the lowland tapir and aardvark were compound alveolar serous secretory units, and in both species, the secretion was composed of neutral and acidic mucopolysaccharides (sialo and sulfated mucins). However, in both the lowland tapir and aardvark, a histological examination found the stroma of the mandibular gland was divided into very large lobes by poorly marked connective tissue. While many interlobar and striated ducts were found in the aardvark, very few were found in the lowland tapir. The mandibular gland was a branched tubular (mucous secretion) type in the lowland tapir, but it was a branched tubuloalveolar (mucous-serous) type in the aardvark. In all tested glands, the secretion was composed of neutral mucopolysaccharides, acid-sulfated mucosubstances, and sialomucins.
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![A Novel Chitosan-[gamma]PGA...](http://api.summon.serialssolutions.com/2.0.0/image/issn/XR4PS5YY4K/1932-6203/small "A Novel Chitosan-[gamma]PGA Polyelectrolyte Complex Hydrogel Promotes Early New Bone Formation in the Alveolar Socket Following Tooth Extraction")
