Wet purpura in Dengue fever Manappallil, Robin George; Yelisetti, Mounika
Asian Journal of Medical Sciences,
03/2018, Volume:
9, Issue:
2
Journal Article
Peer reviewed
Open access
Dengue fever is an acute febrile viral illness associated with severe headache, myalgia, arthralgia, rashes, leucopenia and thrombocytopenia. These patients can present with haemorrhagic ...manifestations. Wet purpura in oral mucosa occurs when there is a drastic fall in platelet counts; and can be taken as a sign of impending systemic haemorrhage. This is the case of a young male who was diagnosed to have Dengue fever. He developed severe thrombocytopenia and wet purpura, following which he had gastrointestinal bleed. Dengue fever presenting with wet purpura is a rare scenario.Asian Journal of Medical Sciences Vol.9(2) 2018 43-44
Wissenstransfer und kooperative Forschung an den Schnittstellen von Universität, Wirtschaft, Politik, Zivilgesellschaft und Kultur gewinnen für alle an Wissensproduktion und Innovationsprozessen ...beteiligten Akteure und Institutionen zunehmend an Relevanz. Schlüsselwörter wie Transferwissenschaften, Transdisziplinarität und transformative Wissenschaft bestimmen inzwischen die wissenschaftstheoretische Debatte, doch bleiben deren konzeptionelle und terminologische Grundlagen vielfach unklar und umstritten. Welche Mehrwerte, Funktionen, Potentiale und Aporien verbinden sich mit der Idee der Transferwissenschaften? Wie verändert sich ihr Stellenwert in der aktuellen wissenschaftlichen Auseinandersetzung? Inwieweit geht sie mit einer Innovation hochschuldidaktischer Methoden einher?
Due of paucity of studies on stress ulcer prophylaxis in intracerebral hemorrhage (ICH), we have evaluated the usefulness of ranitidine and sucralfate in preventing gastric hemorrhage (GH) in ...patients with ICH.
In a hospital-based randomized placebo-controlled study, patients with CT-proven ICH within 7 days of ictus were randomized into ranitidine 50 mg i.v. eight hourly, sucralfate 1 g six hourly and placebo groups. Patients were conservatively managed. Primary endpoint was occurrence of GH within 15 days of ictus and secondary endpoint 1-month mortality.
The mean age of the patients was 57.2 (range 25–90) years and 40 were females. There were 45 patients in ranitidine, 49 in sucralfate and 47 in placebo group. Demographic, clinical and radiological features were not significantly different in 3 groups. GH occurred in 11 (23.4%) patients in placebo, 5 (11.1%) in ranitidine and 7 (14.3%) in sucralfate group, which was not significant. Only one female had GH. There were 13 (27.7%) deaths in placebo, 5 (11.1%) in ranitidine and 12 (24.5%) in sucralfate group. Pneumonia occurred in placebo group in 5 (10.6%), ranitidine in 2 (4.4%) and sucralfate in 5 (10.2%) patients, which was not significantly different.
Ranitidine and sucralfate do not seem to significantly prevent GH or reduce 1-month mortality.
Vascular anomalies involving the small bowel are an uncommon cause of gastrointestinal bleeding in childhood. We present here an 11-year-old boy who presented with severe anemia and malena. The ...routine investigations did not reveal any pathology. A capsule endoscopy study was performed, which clinched the diagnosis and identified two intestinal hemangiomas. The hemangiomas were resected and the child recovered.