A look at the lives of lipids Baskin, Jeremy M.; Seeliger, Jessica C.
Current opinion in chemical biology,
December 2021, 2021-12-00, 20211201, Volume:
65
Journal Article
Editor's Choice: June 2022 Beukeboom, Leo W.
Entomologia experimentalis et applicata,
June 2022, 2022-06-00, 20220601, Volume:
170, Issue:
6
Journal Article
Peer reviewed
Lack of lipid accumulation in two species of chalcidoid wasps with secondarily evolved phytophagy – M. Lammers, K. Kraaijeveld & J. Ellers (https://doi.org/10.1111/eea.13164).
The lipid composition of cellular organelles is tailored to suit their specialized tasks. A fundamental transition in the lipid landscape divides the secretory pathway in early and late membrane ...territories, allowing an adaptation from biogenic to barrier functions. Defending the contrasting features of these territories against erosion by vesicular traffic poses a major logistical problem. To this end, cells evolved a network of lipid composition sensors and pipelines along which lipids are moved by non-vesicular mechanisms. We review recent insights into the molecular basis of this regulatory network and consider examples in which malfunction of its components leads to system failure and disease.
In the Republic of Croatia, hazel (Corylus avellana L) is the fruit species with the largest recorded increase in cultivation. Due to its high content of lipids and moisture (at the time of harvest) ...hazelnuts are susceptible to quality deterioration (rancidity development, mycotoxins contamination etc.) and therefore proper harvest and post-harvest handling is necessary to preserve their quality. Hazelnuts are most often collected from the ground by the appropriate mechanization. After harvesting, proper drying of is a crucial measure. Hazelnuts in the shell should be dried to about 7-10% moisture, and the kernel moisture content should be from about 4 - 6%. The maximum drying temperature should never exceed 50 degreesC. Regarding the storage conditions, the relative humidity is the most important factor and should never exceed 70%, while it is optimal to range from about 55 - 65%. Low temperatures (<10 degreesC) are effective means of prolonging hazelnut storage life because numerous negative processes (rancidity development, microbiological activity, etc.) are notably slowed down. The use of a modified atmosphere (low oxygen concentrations) has also shown to be an effective measure in prolonging storage life.
Elevated cholesterol/lipid levels, especially low-density lipoprotein cholesterol (LDL-C) are known to contribute to the development of atherosclerotic cardiovascular disease (ASCVD). The attainment ...of lipid targets is known to be suboptimal both globally and locally. This study aimed to evaluate the effectiveness of a lipid management pathway (LMP) in supporting attainment of lipid targets following an acute coronary syndrome (ACS) in a local cohort of cardiac rehabilitation (CR) patients.
Quantitative data were retrospectively collected from 54 CR patient records. Local lipid target attainment was benchmarked against national guidelines and pre-pathway implementation audit results.
The number of admission lipid profiles increased by 24.8% to 79.6% following implementation of the LMP. There was a 31% improvement in the number of patients achieving either a 50% reduction in LDL-C or an LDL-C level of <1.4 mmol/L. In conclusion, the LMP had a significant positive impact upon the attainment of lipid goals.
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