“The most exciting thing about my research is that it works! Our machine learning models are general and robust enough to ‘discover’ new chemistry that we have not thought about beforehand, but which ...often makes a lot of sense a posteriori … I celebrate success by starting to think about what to do next.” Find out more about Lukáš Grajciar in his Introducing … Profile.
Machine learning (ML) is a burgeoning field of medicine with huge resources being applied to fuse computer science and statistics to medical problems. Proponents of ML extol its ability to deal with ...large, complex and disparate data, often found within medicine and feel that ML is the future for biomedical research, personalized medicine, computer‐aided diagnosis to significantly advance global health care. However, the concepts of ML are unfamiliar to many medical professionals and there is untapped potential in the use of ML as a research tool. In this article, we provide an overview of the theory behind ML, explore the common ML algorithms used in medicine including their pitfalls and discuss the potential future of ML in medicine.
Emerging technologies and applications including Internet of Things, social networking, and crowd-sourcing generate large amounts of data at the network edge. Machine learning models are often built ...from the collected data, to enable the detection, classification, and prediction of future events. Due to bandwidth, storage, and privacy concerns, it is often impractical to send all the data to a centralized location. In this paper, we consider the problem of learning model parameters from data distributed across multiple edge nodes, without sending raw data to a centralized place. Our focus is on a generic class of machine learning models that are trained using gradient-descent-based approaches. We analyze the convergence bound of distributed gradient descent from a theoretical point of view, based on which we propose a control algorithm that determines the best tradeoff between local update and global parameter aggregation to minimize the loss function under a given resource budget. The performance of the proposed algorithm is evaluated via extensive experiments with real datasets, both on a networked prototype system and in a larger-scale simulated environment. The experimentation results show that our proposed approach performs near to the optimum with various machine learning models and different data distributions.
A long-standing goal of artificial intelligence is an algorithm that learns, tabula rasa, superhuman proficiency in challenging domains. Recently, AlphaGo became the first program to defeat a world ...champion in the game of Go. The tree search in AlphaGo evaluated positions and selected moves using deep neural networks. These neural networks were trained by supervised learning from human expert moves, and by reinforcement learning from self-play. Here we introduce an algorithm based solely on reinforcement learning, without human data, guidance or domain knowledge beyond game rules. AlphaGo becomes its own teacher: a neural network is trained to predict AlphaGo's own move selections and also the winner of AlphaGo's games. This neural network improves the strength of the tree search, resulting in higher quality move selection and stronger self-play in the next iteration. Starting tabula rasa, our new program AlphaGo Zero achieved superhuman performance, winning 100-0 against the previously published, champion-defeating AlphaGo.
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