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  • Optimizing C2C12 myoblast d... Optimizing C2C12 myoblast differentiation using polycaprolactone–polypyrrole copolymer scaffolds
    Browe, Daniel; Freeman, Joseph Journal of biomedical materials research. Part A, January 2019, 2019-01-00, 20190101, Volume: 107, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Advancements in tissue engineering and biomaterial development have the potential to provide a scalable solution to the problem of large‐volume skeletal muscle defects. Previous research on the ...
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42.
  • The classic metal‐sensing t... The classic metal‐sensing transcription factor MTF1 promotes myogenesis in response to copper
    Tavera‐Montañez, Cristina; Hainer, Sarah J.; Cangussu, Daniella ... The FASEB journal, December 2019, Volume: 33, Issue: 12
    Journal Article
    Peer reviewed
    Open access

    Metal‐regulatory transcription factor 1 (MTF1) is a conserved metal‐binding transcription factor in eukaryotes that binds to conserved DNA sequence motifs, termed metal response elements. MTF1 ...
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43.
  • Circ-ZNF609 Is a Circular R... Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis
    Legnini, Ivano; Di Timoteo, Gaia; Rossi, Francesca ... Molecular cell, 04/2017, Volume: 66, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well ...
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44.
  • Heparin-Mimicking Polymer-B... Heparin-Mimicking Polymer-Based In Vitro Platform Recapitulates In Vivo Muscle Atrophy Phenotypes
    Kim, Hyunbum; Jeong, Ji Hoon; Fendereski, Mona ... International journal of molecular sciences, 03/2021, Volume: 22, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    The cell-cell/cell-matrix interactions between myoblasts and their extracellular microenvironment have been shown to play a crucial role in the regulation of in vitro myogenic differentiation and in ...
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45.
  • DNA methyltransferase inhib... DNA methyltransferase inhibitor CDA-II inhibits myogenic differentiation
    Chen, Zirong; Jin, Guorong; Lin, Shuibin ... Biochemical and biophysical research communications, 06/2012, Volume: 422, Issue: 3
    Journal Article
    Peer reviewed

    ► CDA-II inhibits myogenic differentiation in a dose-dependent manner. ► CDA-II repressed expression of muscle transcription factors and structural proteins. ► CDA-II inhibited proliferation and ...
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  • Vascular wall progenitor ce... Vascular wall progenitor cells in health and disease
    Psaltis, Peter J; Simari, Robert D Circulation research, 2015-Apr-10, Volume: 116, Issue: 8
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    Peer reviewed
    Open access

    The vasculature plays an indispensible role in organ development and maintenance of tissue homeostasis, such that disturbances to it impact greatly on developmental and postnatal health. Although ...
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47.
  • Electrically conductive nan... Electrically conductive nanofibers with highly oriented structures and their potential application in skeletal muscle tissue engineering
    Chen, Mei-Chin; Sun, Yu-Chin; Chen, Yuan-Hsiang Acta biomaterialia, 03/2013, Volume: 9, Issue: 3
    Journal Article
    Peer reviewed

    Recent trends in scaffold design have focused on materials that can provide appropriate guidance cues for particular cell types to modulate cell behavior. In this study highly aligned and ...
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  • Musclin is an activity-stim... Musclin is an activity-stimulated myokine that enhances physical endurance
    Subbotina, Ekaterina; Sierra, Ana; Zhu, Zhiyong ... Proceedings of the National Academy of Sciences - PNAS, 12/2015, Volume: 112, Issue: 52
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    Peer reviewed
    Open access

    Exercise remains the most effective way to promote physical and metabolic wellbeing, but molecular mechanisms underlying exercise tolerance and its plasticity are only partially understood. In this ...
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49.
  • Myomerger promotes fusion p... Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm
    Golani, Gonen; Leikina, Evgenia; Melikov, Kamran ... Nature communications, 01/2021, Volume: 12, Issue: 1
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    Peer reviewed
    Open access

    Myomerger is a muscle-specific membrane protein involved in formation of multinucleated muscle cells by mediating the transition from the early hemifusion stage to complete fusion. Here, we ...
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  • High-Dimensional Single-Cel... High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations
    Giordani, Lorenzo; He, Gary J.; Negroni, Elisa ... Molecular cell, 05/2019, Volume: 74, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Adult tissue repair and regeneration require stem-progenitor cells that can self-renew and generate differentiated progeny. Skeletal muscle regenerative capacity relies on muscle satellite cells ...
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