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Serious drug reactions to carbamazepine in oncologic patients after x-ray treatment : report of four casesKansky, Aleksej ; Vodnik-Cerar, Alenka, 1944-2023 ; Stanovnik, LovroCarbamazepine is a valuable and widely used drug for treatment and prevention of epileptiform fits and further neurological conditions. Milder general symptoms like dizziness or drowsiness or ... cutaneous side effects like rashes, pruritus, urticaria, or multiform erythema are not unusual. Sometimes serious cutaneous adverse reactions e.g., Stevens Johnson syndrome, generalized erythroderma or even toxic necrolysis may appear. We report on four cases: in three female patients, who have been operated for malignant brain tumors and were given carbamazepine for prevention of seizures, partial erythroderma developed; the fourth died from toxic epidermal necrolysis. All were treated with x-rays, in the female patients cutaneous manifestations disappeared aftersystemic treatment with corticosteroids and replacement of carbamazepine with other anticonvulsive drugs.Source: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Letn. 11, št. 3, September 2002, str. 105-109)Type of material - article, component partPublish date - 2002Language - englishCOBISS.SI-ID - 15702489
Author
Kansky, Aleksej |
Vodnik-Cerar, Alenka, 1944-2023 |
Stanovnik, Lovro
Topics
Carbamazepine |
Adverse Effects |
Brain Neoplasms |
Radiotherapy |
Adult |
Middle Age |
Dermatitis, Exfoliative |
Exanthema |
Karbamazepin |
Možganske novotvorbe |
Dermatitis eksfoliativni |
Eksantem |
Odrasli |
Srednja leta
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source: Acta dermatovenerologica Alpina, Panonica et Adriatica. - ISSN 1318-4458 (Letn. 11, št. 3, September 2002, str. 105-109)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Kansky, Aleksej | 01174 |
Vodnik-Cerar, Alenka, 1944-2023 | 12198 |
Stanovnik, Lovro | 01547 |
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