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Vloga žilnih in biokemičnih sprememb v krvi pri esencialni arterijski hipertenziji : doktorsko deloŽižek, Bogomir, 1949-Essential arterial hypertension (EAH) is an important risk factor for atherosclerosis. Etiology and pathogenesis of EAH is not known yet. Abnormalities found in patients could be related to the ... underlying cause of EAH or may be only the consequences of long-standing elevated blood pressure. We studied functional and morphological arterial wall abnormalities in hypertonics without evidence of cardiovascular events. The study was focused on biochemical changes, which are thought to be a part of the polymetabolic syndrome and which could have some influence on hemorheology and atherogenesis. In our study we wanted to find arterial wall and blood structure changes that are characteristic for the group of individuals with hypertnesive familial trait. Thickness of the intima and media (IMT) of the carotid arteries and changes in the blood flow and the diameter of the brachial artery (flow-dependent) dilation (FMD) were measured. IMT was measured by B-mode ultrasound, while dilation of peripheral artery was evaluated by the provocation test occuring during reactive hyperaemia and after administration of glyceriltrinitrate. 46 hypertonics (mean age 49 years)without evidence of major cardiovascular events, were divided into two subgroups. In the first grou there were 22 hypertonics treated with Ca-channelblockers and in the second group 24 patients treated with angiotensin converting enzyme inhibitors. 44 healthy normotensive and age-matched subjects served as controls. We also tested 41 offspring (familialtrait-FT) of subjects with EH (mean age 25 years) and 41 age- and sex-matched controls without FT. (Abstract truncated at 2000 characters.)Type of material - dissertation ; adult, seriousPublication and manufacture - Ljubljana : [B. Žižek], 1999Language - slovenianCOBISS.SI-ID - 1976340
Author
Žižek, Bogomir, 1949-
Other authors
Poredoš, Pavel
Topics
Arterijska hipertenzija, esencialna |
Disertacije |
Hypertension |
Physiopathology |
Hypertension |
Blood |
Carotid arteries |
Ultrasonography |
Brachial artery |
Physiology |
Hipertenzija |
Patofiziologija |
Hipertenzija |
Kri |
Karotidne arterije |
Ultrasonografija |
Brahialna arterija |
Fiziologija |
arterijska hipertenzija |
etiopatogeneza |
periferne arterije |
kri |
ateroskleroza
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Library | Call number – location, accession no. ... | Copy status |
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National and University Library, Ljubljana | GS II 505661 glavno skladišče | available - reading room |
MF, Central Medical Library, Lj. | doktorske disertacije ŽIŽEK BOGOMIR Vloga IN: 099900527 |
available - outside loan, loan period: 1 months |
MF, Central Medical Library, Lj. | doktorske disertacije ŽIŽEK BOGOMIR Vloga IN: 099900526 |
available - outside loan, loan period: 1 months |
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Database name | Field | Year |
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Žižek, Bogomir, 1949- | 17901 |
Poredoš, Pavel | 04548 |
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