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  • The response of peripheral blood mononuclear cells to shape memory alloys [Elektronski vir]
    Rudolf, Rebeka ...
    The aim of this work was to study the response of human peripheral blood mononuclear cells (PB-MNCs) to Cu-Al-Ni and Ni-Ti shape memory alloys (SMAs). The alloys were prepared as rapidly solidified ... thin ribbons via melt spinning. It has been shown that the ribbons were non cytotoxic for PB-MNCs as determined by the viability and apoptosis assay. In 18 cultures out of 20 cultures of individual donor PB-MNCs cultivated with Cu-Al-Ni SMAs, no significant changes in the production of Th1 (IFN-▫$\gamma$▫), Th2 (IL-5 and IL-10) and proinflammatory (IL-1▫$\beta$▫, TNF-▫$\alpha$▫, IL-6 and IL-8) cytokines were detected compared to controls. In two cultures out of 20, a significant increase in the production of Th1 and proinflammatory cytokines was observed. Microstructural analyses confirmed the formation of thin oxide on the surface of both SMA ribbons.
    Source: International journal of immunological studies [Elektronski vir]. - ISSN 1754-145X (Vol. 1, no. 2, 2010, str. 214-228)
    Type of material - e-article
    Publish date - 2010
    Language - english
    COBISS.SI-ID - 14329366
    DOI

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