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  • Programmed self-assembly of a quadruplex DNA nanowire
    Hessari, Nason Ma'ani ...
    The ability to produce, reproducibly and systematically, well-defined quadruplex DNA nanowires through controlled rational design is poorly understood despite potential utility in structural ... nanotechnology. The programmed hierarchical self-assembly of a long four-stranded DNA nanowire through cohesive self-assembly of GpC and CpG "sticky" ends is reported. The encoding of bases within the quadruplex stem allows for an uninterrupted ▫$\pi$▫-stacking system with rectilinear propagation for hundreds of nanometers in length. The wire is mechanically stable and features superior nuclease resistance to double-stranded DNA. The study indicates the feasibility for programmed assembly of uninterrupted quadruplex DNA nanowires. This is fundamental to the systematic investigation of well-defined DNA nanostructures for uses in optoelectronic and electronic devices as well as other structural nanotechnology applications.
    Source: Chemistry : a European journal. - ISSN 0947-6539 (Vol. 20, issue 13, 2014, str. 3626-3630)
    Type of material - article, component part
    Publish date - 2014
    Language - english
    COBISS.SI-ID - 2644580

source: Chemistry : a European journal. - ISSN 0947-6539 (Vol. 20, issue 13, 2014, str. 3626-3630)

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