(UM)
-
Dietary spermidine for lowering high blood pressure [Elektronski vir]Eisenberg, Tobias ...Loss of cardiac macroautophagy/autophagy impairs heart function, and evidence accumulates that an increased autophagic flux may protect against cardiovascular disease. We therefore tested the ... protective capacity of the natural autophagy inducer spermidine in animal models of aging and hypertension, which both represent major risk factors for the development of cardiovascular disease. Dietary spermidine elicits cardioprotective effects in aged mice through enhancing cardiac autophagy and mitophagy. In salt-sensitive rats, spermidine supplementation also delays the development of hypertensive heart disease, coinciding with reduced arterial blood pressure. The high blood pressure-lowering effect likely results from improved global arginine bioavailability and protection from hypertension-associated renal damage. The polyamine spermidine is naturally present in human diets, though to a varying amount depending on food type and preparation. In humans, high dietary spermidine intake correlates with reduced blood pressure and decreased risk of cardiovascular disease and related death. Altogether, spermidine represents a cardio- and vascular-protective autophagy inducer that can be readily integrated in common diets.Source: Autophagy [Elektronski vir]. - ISSN 1554-8635 (Vol. 13, no. 4, 2017, str. 767-769)Type of material - e-articlePublish date - 2017Language - englishCOBISS.SI-ID - 29622275
Author
Eisenberg, Tobias |
Abdellatif, Mahmoud |
Zimmermann, Andreas, medicina |
Schroeder, Sabrina |
Pendl, Tobias |
Harger, Alexandra |
Stekovic, Slaven |
Schipke, Julia |
Magnes, Christoph |
Schmidt, Albrecht, medicina |
Sedej, Simon, 1974-
Topics
aging |
autophagy |
hypertension |
polyamine |
spermidine
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Eisenberg, Tobias | |
Abdellatif, Mahmoud | |
Zimmermann, Andreas, medicina | |
Schroeder, Sabrina | |
Pendl, Tobias | |
Harger, Alexandra | |
Stekovic, Slaven | |
Schipke, Julia | |
Magnes, Christoph | |
Schmidt, Albrecht, medicina | |
Sedej, Simon, 1974- | 20340 |
Source: Personal bibliographies
and: SICRIS
Select pickup location:
Material pickup by post
Delivery address:
Address is missing from the member's data.
The address retrieval service is currently unavailable, please try again.
By clicking the "OK" button, you will confirm the pickup location selected above and complete the reservation process.
By clicking the "OK" button, you will confirm the above pickup location and delivery address, and complete the reservation process.
By clicking the "OK" button, you will confirm the address selected above and complete the reservation process.
Notification
Automatic login and reservation service currently not available. You can reserve the material on the Biblos portal or try again here later.
Subject headings in COBISS General List of Subject Headings
Select pickup location
The material from the parent unit is free. If the material is delivered to the pickup location from another unit, the library may charge you for this service.
Pickup location | Material status | Reservation |
---|
Reservation in progress
Please wait a moment.
Reservation was successful.
Reservation failed.
Reservation...
Membership card:
Pickup location: