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  • Separation of parthenolide from feverfew: performance of conventional and high-pressure extraction techniques
    Čretnik, Lucija ; Škerget, Mojca ; Knez, Željko
    In present work the extraction of feverfew flower heads was performed using supercritical carbon dioxide at pressures from 200 to 800 bar and at temperatures of 40, 60 and 80 °C. For comparison, the ... conventional extractionswith organic solvents have been performed. Dry feverfew flower heads were used as starting material. Supercritical fluid extraction (SFE) wasperformed using a semi continuous flow apparatus in a laboratory and pilot scale. The influence of process parameters on the total yield and amount of parthenolide isolated was investigated. Dynamic behaviour of the extraction runs followed by single-step separation was analysed by a mathematical model for initial constant rate extraction period and the subsequent time-dependant diffusion controlling mass transfer rate period. In order to concentrate the obtained extract in parthenolide, a two-step separation was employed.
    Source: Separation and purification technology. - ISSN 1383-5866 (41, iss. 1, Jan. 2005, str. 13-20)
    Type of material - article, component part
    Publish date - 2005
    Language - english
    COBISS.SI-ID - 9103894

    Link(s):

    http://dx.doi.org/10.1016/j.seppur.2004.03.011
    Digital Library of the University of Maribor – DLUM

source: Separation and purification technology. - ISSN 1383-5866 (41, iss. 1, Jan. 2005, str. 13-20)

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