The purpose of the study was to research the quantitative composition and sensibility to antibiotics of aerobic and anaerobic microorganisms in mouth cavity liquid and parodontal pockets in elderly patients with chronical inflammatory diseases of parodont, namely in patients with chronic cataral gingivitis (38 patients), chronic generalized parodontitis (ChQP; 32 patients, easy form) and in patients with ChQP (34 patients) with relatively heavy form. It was established the increases of quantity microorganisms in mouth cavity liquid of patient all of groups in comparison with healthy group. First of all, it was depended mainly from clinical severity of pathological processes. Simultaneously it was observed association of parodontopathogenic microorganisms in patients of all groups and high variability their association, both susceptibility and resistance to antibiotics, used in stomatological practice.