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Kwon, Soon‐Hyo; Na, Jung‐Im; Choi, Ji‐Young; Park, Kyoung‐Chan
Experimental dermatology, June 2019, Volume: 28, Issue: 6Journal Article
Management of melasma is highly challenging due to inconsistent treatment results and frequent relapses. However, recent studies revealed that melasma may not only be a disease of melanocytes, but also a photoaging skin disorder. Herein, we attempt to validate that melasma is indeed a photoaging disorder by presenting the histopathologic findings of melasma: solar elastosis, altered basement membrane, increased vascularization and increased mast cell count. We also provide some therapeutic implications based on these findings and a discussion on the latest updates and perspectives regarding treatment.
