E-resources
Peer reviewed
-
Nemani, Ajay; Lowe, Mark J.
Medical physics (Lancaster), October 2021, 2021-10-00, 20211001, Volume: 48, Issue: 10Journal Article
Purpose Ultrahigh field (UHF) resting state functional magnetic resonance imaging (rsfMRI) has become increasingly available for clinical and basic research, bringing improvements in resolution and contrast over standard high field imaging. Despite these improvements, UHF connectivity studies present several challenges, including increased sensitivity to physiological confounds and a vastly increased data burden. We present a direct quantitative assessment of test–retest reliability of functional connectivity in several standard functional networks between subjects scanned at 3T and 7T. Methods Five healthy subjects were scanned over four sessions each in a scan‐rescan design at both 3T and 7T field strengths. Resting state fMRI data were segmented into four major intrinsic connectivity networks, and seed‐based peak correlations within and between these networks examined. The reliability of these correlations was assessed using intra‐class correlation coefficients (ICC). Results Across all data, over 4000 peak correlations were extracted for assessment. The reliability over all intrinsic networks was greater at 7T than 3T (median ICC 0.40 vs. 0.33, p ≤ 0.0014), with each network individually showing improvement. Inter‐network reliability was stronger than intra‐network reliability, but intra‐network reliability showed the greatest improvement between field strengths. Conclusion We demonstrate significantly increased reliability of resting state connectivity at UHF strengths over conventional field strengths using a novel hybrid seed‐based analysis. This result adds to the growing body of work supporting the migration of functional imaging studies to UHFs.
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.