A bstract The LHCb collaboration has recently performed a measurement of the production rate of inclusive B hadron production ( pp → BX ) at both 7 and 13 TeV centre-of-mass (CoM) energies. As part of this measurement, the ratio of these two cross section measurements has been presented differentially in B hadron pseudorapidity within the range of η B ∈ 2 . 0 , 5 . 0. A large tension (4 σ ) is observed for the ratio measurement in the lower pseudorapidity range of η B ∈ 2 . 0 , 3 . 0, where the data is observed to exceed theoretical predictions, while consistency is found at larger η B values. This behaviour is not expected within perturbative QCD, and can only be achieved by introducing ad-hoc features into the structure of the non-perturbative gluon PDF within the region of x ∈ 10 −3 , 10 −4 . Specifically, the gluon PDF must grow extremely quickly with decreasing x within this kinematic range, closely followed by a period of decelerated growth. However, such behaviour is highly disfavoured by global fits of proton structure. Further studies of the available LHCb B and D hadron cross section data, available for a range of CoM energies, indicate systematic tension in the (pseudo)rapidity region of 2 . 0 , 2 . 5.