Spatial epigenome–transcriptome comapping technology

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Spatial epigenome–transcriptome comapping technology

Jin, Ming-Zhu; Jin, Wei-Lin

Trends in cell biology, June 2023, 2023-06-00, 20230601, Volume: 33, Issue: 6

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Spatial omics facilitate an in-depth understanding of cell states and cell interactions. Recent work by Zhang et al. simultaneously seizes spatial epigenetic priming, differentiation, and gene regulation at nearly single-cell resolution by developing an epigenome–transcriptome comapping technology. This work displays how epigenetic features influence cell dynamics and transcriptional phenotypes at spatial and genome-wide levels.

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