Can we decondition TRIKAFTA® tablets for the younger ones?

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Can we decondition TRIKAFTA® tablets for the younger ones?

Gabsi, Asma; Benaboud, Sihem; Pouradier, Delphine; Reix, Philippe; L'Excellent, Sophie; Weiss, Laurence; Le-Clainche, Laurence; Dalphin, Marie-Laure; Perisson, Caroline; Deneuville, Eric; Bonnel, Anne Sophie; Sermet-Gaudelus, Isabelle

Journal of cystic fibrosis, March 2024, 2024-Mar, 2024-03-00, 20240301, Volume: 23, Issue: 2

Journal Article

•TRIKAFTA® tablets for children aged 6 years and older.•Difficulties swallowing tablets, eating disorders.•Clinical response of TRIKAFTA® when deconditioned.•Pharmacological assays of peak and residual plasma ETI levels.•TRIKAFTA®’s efficacy when deconditioned.

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