Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy

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Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacy

Loi, Sherene

Oncoimmunology, 07/2013, Volume: 2, Issue: 7

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By analyzing over 2000 samples from a randomized clinical trial, we have recently associated high levels of tumor-infiltrating lymphocytes with an excellent prognosis among triple negative breast cancer patients as well with improved clinical responses to immunogenic chemotherapy among patients bearing HER2 over-expression. These findings suggest that immunomodulation could represent a new approach to treat these aggressive breast cancer subtypes.

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Loi, Sherene

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