Role of thrombin signalling in platelets in haemostatis and thrombosis

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Role of thrombin signalling in platelets in haemostatis and thrombosis

Sambrano, Gilberto R; Weiss, Ethan J; Yao-Wu, Zhang; Huang, Wei; Coughlin, Shaun R

Nature (London), 09/2001, Volume: 413, Issue: 6851

Journal Article

Platelets are critical in haemostasis and in arterial thrombosis, which causes heart attacks and other events triggered by abnormal clotting. The coagulation protease thrombin is a potent activator of platelets ex vivo.

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Sambrano, Gilberto R | Weiss, Ethan J | Yao-Wu, Zhang | Huang, Wei | Coughlin, Shaun R

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