E-resources
Peer reviewed
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Zhang, Dong‐Yang; Zhang, Ying; Wu, Hua; Gong, Liu‐Zhu
Angewandte Chemie (International ed.), May 27, 2019, Volume: 58, Issue: 22Journal Article
An enantioselective catalytic alkoxylation/oxidative rearrangement of allylic alcohols has been established by using a Brønsted acid and chiral organoiodine. The presence of 20 mol % of an (S)‐proline‐derived C2‐symmetric chiral iodine led to enantioenriched α‐arylated β‐alkoxylated ketones in good yields and with high levels of enantioselectivity (84–94 % ee). Shifting positions: Asymmetric catalytic alkoxylation/oxidative rearrangement of allylic alcohols was achieved by using a Brønsted acid and a chiral organoiodine. The reaction leads to optically active α‐arylated β‐etherized ketones in good yields and excellent stereoselectivity. Ts=4‐toluenesulfonyl.
