•Fuel aridity and high-risk fire weather have increased substantially since 1956•The trends are more severe during April-June and linked to the climate change•Fuel aridity levels explain 70% of interannual variability in number of wildfires•Marked increase in wildfire-conducive conditions is expected by 2050•Forested areas above 500 m asl. are expected to see largest increases The occurrence of major wildfires in countries such as Portugal, Italy and Spain (2017) and Sweden (2018) indicated that wildfires pose a risk across Europe. While Central Europe has not been at the center of such events, observed climate data and climate projections suggest a tendency toward more years with wet and warm winters and dry and hot summers as well as fuel accumulation, leading to more hazardous conditions. Although some existing studies analyzed the differences in wildfire occurrence in this territory based on terrain, soil or vegetation characteristics, the effects of climate change have not been properly appraised. To fill this knowledge gap, we used and tested an ensemble of nine fuel aridity metrics, including three dedicated fire danger rating indices, and evaluated their level of agreement with actual fire occurrence, their ability to explain the interannual variability in wildfire frequency, and their temporal trends. The analysis covered the entire territory of the Czech Republic at 500 m spatial resolution. Two periods were included based on observed (1956–2015) and projected (2020–2100) meteorological data using ensembles of five regional climate models (RCMs) and five global circulation models (GCMs) based on Euro-CORDEX and CMIP5 datasets. For the future, we considered Representative Concentration Pathway (RCP) 4.5. Our results showed that since 1956, most of the Czech territory has exhibited an increasing frequency of fire weather days (i.e., days with highly conducive wildfire conditions) and an increasing area affected by weather conducive to wildfire occurrence, with the trends accelerating after 2000. The annual variation in the fuel aridity levels (derived solely from meteorological data) explained more than 2/3 of the reported wildfire variability during 1991–2015 over the Czech Republic. The future projections based on the RCM or GCM ensembles indicated a significant increase in fuel aridity and an increase in the area under fire-conducive conditions. Recommendations derived from such robust results are provided for stakeholders seeking to implement adaptation measures. Display omitted