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Afify, Ahmed F.; Hassanien, Rabab T.; El Naggar, Rania F.; Rohaim, Mohammed A.; Munir, Muhammad
Microbial pathogenesis, August 2024, 2024-08-00, 20240801, Volume: 193Journal Article
Equid herpesviruses (EHVs) are a group of highly impactful viral pathogens that affect horses, presenting a substantial risk to the global equine industry. Among these, equid herpesvirus-1 (EHV-1) primarily causes respiratory infections. However, its ability to spread to distant organs can lead to severe consequences such as abortion and neurological diseases. These viruses can enter a dormant phase, with minimal activity, and later reactivate to trigger active infections at any time. Recently, there has been a notable rise in the prevalence of a particularly devastating strains of EHV-1 known as equid herpesviral myeloencephalopathy (EHM). In the light of dynamic nature of EHV-1, this review provides a thorough overview of EHV-1 and explores how advances in viral biology affect the pathophysiology of viral infection. The information presented here is crucial for understanding the dynamics of EHV-1 infections and creating practical plans to stop the virus's global spread among equid populations. •Equine herpesviruses (EHVs) are a group of highly impactful viral pathogens of equines.•Recently, a strain of EHV-1 reported to cause equine herpes viral myeloencephalopathy (EHM).•We highlight advancements in EHV and EHM management in horses.•Dynamics of EHV-1 infections and strategies to control its spread are discussed.•We emphasis the monitoring of recombinant strain of EHV-1 in equines.
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