UNI-MB - logo
UMNIK - logo
 
E-resources
Peer reviewed Open access
  • The COVID-19 Cytokine Storm...
    Ragab, Dina; Salah Eldin, Haitham; Taeimah, Mohamed; Khattab, Rasha; Salem, Ramy

    Frontiers in immunology, 06/2020, Volume: 11
    Journal Article

    COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract resulting in pneumonia in most of the cases and acute respiratory distress syndrome (ARDS) in about 15 % of the cases. Mortality in COVID-19 patients has been linked to the presence of the so-called "cytokine storm" induced by the virus. Excessive production of proinflammatory cytokines leads to ARDS aggravation and widespread tissue damage resulting in multi-organ failure and death. Targeting cytokines during the management of COVID-19 patients could improve survival rates and reduce mortality.