Molecular morphogens for dendritic spines

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Molecular morphogens for dendritic spines

Ehlers, Michael D

Trends in neurosciences (Regular ed.), 02/2002, Volume: 25, Issue: 2

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Three protein components of the postsynaptic density – Shank, Homer and SPAR – have been found to regulate the structural and molecular organization of dendritic spines. These new studies reveal linkages between receptor complexes, the actin cytoskeleton and signaling molecules that help shape spines. New insights into the molecular control of spine shape and composition: the postsynaptic proteins Shank, Homer and SPAR help to organize spines

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