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  • A Chiral Bis(betaine) Catal...
    Zhang, Wen-Quan; Cheng, Ling-Feng; Yu, Jie; Gong, Liu-Zhu

    Angewandte Chemie (International ed.), April 23, 2012, Volume: 51, Issue: 17
    Journal Article

    By design: New chiral bis(betaine)s, for example 1, containing two catalytically active centers have been designed. They have proven to be promising organocatalysts for the direct Mannich‐type reaction of azlactones with a broad spectrum of aliphatic imines, thus affording α‐tetrasubstituted α,β‐diamino acid surrogates with excellent enantioselectivities.