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Singh, Gagandeep; Abbad, Anass; Kleiner, Giulio; Srivastava, Komal; Gleason, Charles; Carreño, Juan Manuel; Simon, Viviana; Krammer, Florian
MBio, 01/2024, Volume: 15, Issue: 1Journal Article
As demonstrated by severe acute respiratory syndrome coronavirus 2, coronaviruses pose a significant pandemic threat. Here, we show that coronavirus disease 2019 mRNA vaccination can induce significant levels of cross-reactive antibodies against diverse coronavirus spike proteins. While these antibodies are binding antibodies that likely have little neutralization capacity and while their contribution to cross-protection is unclear, it is possible that they may play a role in protection from progression to severe disease with novel coronaviruses.
