Research and policy have invested in the prospect that gaining digital skills enhances children’s and young people’s outcomes. A systematic evidence review of research on digital skills among 12- to 17-year-olds identified 34 studies that used cross-sectional survey methods to examine the association of digital skills with tangible outcomes. Two-thirds concerned the association with online opportunities or other benefits. Another third examined online risks of harm. Findings showed a positive association between digital skills and online opportunities, information benefits, and orientation to technology. Greater digital skills were indirectly linked to greater exposure to online risks, although any link to harm was unclear. While technical skills were linked with mixed or even negative outcomes, information skills were linked with positive outcomes. There was little research on the outcomes of communication or creative digital skills. Future research should examine the dimensions of digital skills separately and encompass a wider range of outcomes.