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De Giovanni, Carla; Nicoletti, Giordano; Landuzzi, Lorena; Palladini, Arianna; Lollini, Pier-Luigi; Nanni, Patrizia
Cancers, 11/2019, Volume: 11, Issue: 12Journal Article
The TS/A cell line was established in 1983 from a spontaneous mammary tumor arisen in an inbred BALB/c female mouse. Its features (heterogeneity, low immunogenicity and metastatic ability) rendered the TS/A cell line suitable as a preclinical model for studies on tumor-host interactions and for gene therapy approaches. The integrated biological profile of TS/A resulting from the review of the literature could be a path towards the description of a precision experimental model of mammary cancer.
