E-resources
Peer reviewed
Open access
-
Madrigal-Burgaleta, Ricardo; Alvarez-Cuesta, Emilio; Madrigal-Burgaleta, Ricardo; Broyles, Ana D.; Cuesta-Herranz, Javier; Guzman-Melendez, Maria Antonieta; Maciag, Michelle C.; Phillips, Elizabeth J.; Trubiano, Jason A.; Wong, Johnson T.; Ansotegui, Ignacio; Ali, F. Runa; Angel-Pereira, Denisse; Banerji, Aleena; Berges-Gimeno, Maria Pilar; Bernal-Rubio, Lorena; Brockow, Knut; Cardona Villa, Ricardo; Castells, Mariana C.; Caubet, Jean-Christoph; Chang, Yoon-Seok; Ensina, Luis Felipe; Chikhladze, Manana; Chiriac, Anca Mirela; Chung, Weng-Hung; Ebisawa, Motohiro; Fernandes, Bryan; Garvey, Lene Heise; Gomez, Maximiliano; Gomez Vera, Javier; Gonzalez Diaz, Sandra; Hong, David I.; Ivancevich, Juan Carlos; Kang, Hye-Ryun; Khan, David A.; Kuruvilla, Merin; Larco Sousa, Jose Ignacio; Latour-Staffeld, Patricia; Liu, Anne Y.; Macy, Eric; Malling, Hans Jorgen; Maspero, Jorge; May, Sara M.; Mayorga, Cristobalina; Park, Miguel A.; Peter, Jonathan; Picard, Matthieu; Rodriguez-Bouza, Tito; Romano, Antonino; Sanchez-Borges, Mario; Tanno, Luciana Kase; Torres, Maria Jose; Ureña-Tavera, Alicia; Valluzzi, Rocco L.; Volcheck, Gerald W.; Yamaguchi, Masao
The World Allergy Organization journal, 06/2022, Volume: 15, Issue: 6Journal Article
Drug hypersensitivity reactions (DHRs) to intravenous drugs can be severe and might leave patients and doctors in a difficult position where an essential treatment or intervention has to be suspended. Even if virtually any intravenous medication can potentially trigger a life-threatening DHR, chemotherapeutics, biologics, and antibiotics are amongst the intravenous drugs most frequently involved in these reactions. Admittedly, suspending such treatments may negatively impact the survival outcomes or the quality of life of affected patients. Delabeling pathways and rapid drug desensitization (RDD) can help reactive patients stay on first-choice therapies instead of turning to less efficacious, less cost-effective, or more toxic alternatives. However, these are high-complexity and high-risk techniques, which usually need expert teams and allergy-specific techniques (skin testing, in vitro testing, drug provocation testing) to ensure safety, an accurate diagnosis, and personalized management. Unfortunately, there are significant inequalities within and among countries in access to allergy departments with the necessary expertise and resources to offer these techniques and tackle these DHRs optimally. The main objective of this consensus document is to create a great benefit for patients worldwide by aiding allergists to expand the scope of their practice and support them with evidence, data, and experience from leading groups from around the globe. This statement of the Drug Hypersensitivity Committee of the World Allergy Organization (WAO) aims to be a comprehensive practical guide on the technical aspects of implementing acute-onset intravenous hypersensitivity delabeling and RDD for a wide range of drugs. Thus, the manuscript does not only focus on clinical pathways. Instead, it also provides guidance on topics usually left unaddressed, namely, internal validation, continuous quality improvement, creating a healthy multidisciplinary environment, and redesigning care (including a specific supplemental section on a real-life example of how to design a dedicated space that can combine basic and complex diagnostic and therapeutic techniques in allergy).
Author
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
If the library membership card is not in the list,
add a new one.
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|
Source: Personal bibliographies
and: SICRIS
The material is available in full text. If you wish to order the material anyway, click the Continue button.