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Gosselink, Kristin L; Fonseca, Jorge A Sierra; Jezova, Daniela
Frontiers in behavioral neuroscience, 11/2022, Volume: 16Journal Article
Bertholomey et al. confirm that control adult female rats display less anxiety-like behavior than males in an elevated plus maze. Chronic corticosterone (Cort) exposure, which partially mimics a chronic stress condition, had no impact on anxiety measures but increased immobility in the forced swim test, a behavioral marker of depression, in an age- and sex-specific manner. Collectively, the articles in this Research Topic give a wide view of chronic stress models, their impact on excitability in the brain, and their potential contribution to the development of increased anxiety or other conditions of impaired mental health.
