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Sakamoto, Sachiko; Oiso, Naoki; Emoto, Masakatsu; Uchida, Shusuke; Hirao, Ayaka; Tatsumi, Yoichi; Matsumura, Itaru; Kawada, Akira
Case reports in dermatology, 03/2012, Volume: 4, Issue: 1Journal Article
Patients with hematologic malignancies are immunosuppressive and may develop cutaneous or invasive infections as a primary sign of immune suppression. Acute promyelocytic leukemia (acute myeloid leukemia M3) is caused by translocation of reciprocal chromosomal rearrangement t(15;17), which produces an oncogenic protein. We herein describe a 71-year-old man having cellulitis with leukocytopenia as a first sign of acute promyelocytic leukemia. Dermatologists and hematologists should keep in mind that patients with a hematologic malignancy, such as acute promyelocytic leukemia, can develop cellulitis with leukocytopenia.
