In the present work, the novel anodic oxide film (AOF) with self-sealing layer was successfully fabricated on 2024Al alloys by using an improved anodic oxidation method. The presence of the self-sealing layer on the porous layer of AOF was verified by Field emission scanning electron micro scope. Confocal laser scanning microscope (CLSM) and X-ray photoelectron spectroscopy (XPS) were used to evaluate the morphology and the corrosion products of the AOF after salt spray test. The microhardness test showed that the self-sealing AOFs still displayed high hardness even after salt spray test. Electrochemical test and salt spray test results illustrated the excellent corrosion performance of the novel structured self-sealing anodic oxide film (SAOF) compared with common porous AOFs. The narrow diameter makes it difficult for chlorine ions ingress into the pores of SAOFs. The self-sealing layer played an important role in protecting the SAOF from corrosion.